Results 171 to 180 of about 26,050 (260)

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng   +7 more
wiley   +1 more source

Steps Toward Vitrification and Banking of Coral Larvae Using Field‐Friendly Cryomesh Technology

open access: yesAdvanced Science, EarlyView.
Cryomesh enables a low‐tech cryopreservation method, adding a valuable option to the coral reef conservation toolkit. The approach reveals how size, toxicity, and developmental stage govern larval survival, while modeling links cooling and rewarming rates to a theoretical upper volume limit.
E. Michael Henley   +15 more
wiley   +1 more source

Rethinking Cochlear Implants: The Need for Precise Temporal Coding

open access: yesAdvanced Science, EarlyView.
Spatial hearing relies on sensitivity to interaural temporal cues, but this sensitivity is often poorly developed in patients with cochlear implants, particularly those with early‐onset hearing loss. Rats with cochlear implants, however, demonstrate excellent temporal sensitivity, suggesting that this limitation is not inevitable.
Nicole Rosskothen‐Kuhl   +1 more
wiley   +1 more source

Strain‐Enhanced Ultrastretchable Semiconducting Polymer Fibers for Organic Electrochemical Transistors

open access: yesAdvanced Science, EarlyView.
The continuous fabrication of stretchable polymer semiconductor p(g2T‐T) fibers is realized via wet‐spinning. The p(g2T‐T) semiconductor fibers possess an efficient strain energy dissipation mechanism and unique strain‐enhanced electrical performance. They can be stretched to over 250% strain and exhibit an ultrahigh normalized transconductance of 276 ...
Zixu Chang   +8 more
wiley   +1 more source

SynAtlas: A Safe and Versatile Platform for Rapid Organ‐Scale Tissue Clearing and 3D Atlas Mapping

open access: yesAdvanced Science, EarlyView.
An orthogonal synergy design principle integrates lipid solubilization, protein hydration modulation, and refractive‐index matching within a unified aqueous clearing system. This modular strategy enables rapid, low‐hazard, and broadly compatible tissue clearing while preserving molecular signals, supporting multiscale three‐dimensional imaging across ...
Mei‐Xue Yuan   +10 more
wiley   +1 more source

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