Results 41 to 50 of about 274,455 (317)
It is difficult to predict the earthquake loading so the effect of pre-strain on fatigue strength was required to investigate. Especially, surface shape was changed when large plastic strain was applied.
Shota HASUNUMA +2 more
doaj +1 more source
What is behind the plastic strain rate? [PDF]
Rheologica Acta, 48 (7)
Hütter, Markus +2 more
openaire +3 more sources
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Research on the Accumulated Plastic Strain of Expansive Soil under Subway Loading
Expansive soil near Hefei Xinqiao International Airport was selected as the research focus. The effects of different loading modes on the dynamic strain of the saturated remodeled expansive soil was investigated by indoor dynamic triaxial tests and the ...
Lei Zhu +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Thin-walled laminated cooling plates integrate internal channels and pin-fin cores, producing reduced and spatially non-uniform stiffness that changes welding restraint and distortion. This study investigates stiffness-controlled plastic-strain evolution
Chengkun Li +7 more
doaj +1 more source
Plastic deformation behavior and constitutive modeling of Cu-50Ta alloy during hot compression
This paper presents a study on plastic deformation behavior of Cu–50Ta alloy at temperatures of 286–473 K and strain-rate of 0.01–6200 s ^−1 . The effects of temperature, strain-rate, and strain on the yield strength, flow stress, and strain-rate ...
Bo Pu +4 more
doaj +1 more source
Quasistatic Nonassociative Plasticity at Finite Strains
We investigate finite-strain elastoplastic evolution in the nonassociative setting. The constitutive material model is formulated in variational terms and coupled with the quasistatic equilibrium system. We introduce measure-valued energetic solutions and prove their existence via a time discretization approach.
Stefanelli, Ulisse, Vikelis, Andreas
openaire +4 more sources
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

