Results 51 to 60 of about 657,951 (302)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Determination of micro-scale plastic strain caused by orthogonal cutting [PDF]

, 2008
An electron beam lithography technique has been used to produce microgrids in order to measure local plastic strains, induced during an orthogonal cutting process, at the microscopic scale in the shear zone and under the machined surface. Microgrids with
Allais, Altintas, Beynon, Bitans, C. Pinna, Childs, Delaire, H. Ghadbeigi, Hernandez Castillo, Iwata, J.R. Yates, Jeelani, Jeelani, Karimi, Koshelev, Kurt, Lee, Lin, Madhavan, Mamalis, Merchant, Ng, Obata, Palmer, Pinna, S.R. Bradbury, Sadat, Sadat, Shet, Shih, Sun, Zhang   +31 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

In situ digital image speckle correlation (DISC) observation of plastic strain increment in low-carbon steel

Metalurgija, 2021
The present work is aimed at studying the macroscopic localization of plastic strain in low-carbon steel AISI A283 Grade C. The evolution of macroscopically localized plastic strain at various stages of strain hardening is visualized via a Digital image ...
Yu. Li, S. Barannikova
doaj  

Behaviour of steel fibre reinforced concrete under cyclic compressive loading [PDF]

, 2006
An experimental study was carried out to investigate the behaviour of steel fibre reinforced concrete under cyclic compressive loading. Cylindrical specimens containing two volume fractions (one percent and two percent) of steel fibres and plain concrete
Choubey, U. B., Shukla, Mukesh
core  

Dimpling process in cold roll metal forming by finite element modelling and experimental validation [PDF]

, 2014
The dimpling process is a novel cold-roll forming process that involves dimpling of a rolled flat strip prior to the roll forming operation. This is a process undertaken to enhance the material properties and subsequent products’ structural performance ...
Castellucci, M A, English, M A, Mynors, D J, Nguyen, V B, Wang, C J   +4 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

An elastoplastic framework for granular materials becoming cohesive through mechanical densification. Part II - the formulation of elastoplastic coupling at large strain

, 2010
The two key phenomena occurring in the process of ceramic powder compaction are the progressive gain in cohesion and the increase of elastic stiffness, both related to the development of plastic deformation.
Alessandro Gajo, Andrea Piccolroaz, Bigoni, Bigoni, Bigoni, Borja, Callari, Davide Bigoni, Gajo, Hill, Hill, Hill, Hill, Hoger, Ibrahimbegovic, Itskov, Lee, Ogden, Ortiz, Peric, Petryk, Petryk, Rouainia, Sansour, Schieck, Simo, Simo, Truesdell, Willis   +28 more
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Experimental and Numerical Simulation on the Generation and Development of Cumulative Plastic Strain of Cement Sheath in Salt Cavern Gas Storage Well

Energy Science & Engineering
Salt cavern gas storage is an important technical means to balance the demand for staggered energy supply. Due to the repeated injection and extraction of natural gas in gas storage facilities, sealing integrity failure in the wellbore of gas storage ...
Zhenkun Ren, Yan Xi, Hailong Jiang, Qian Li, Qing Li   +4 more
doaj   +1 more source