Results 11 to 20 of about 11,660 (194)

Estradiol Activates PI3K/Akt/GSK3 Pathway Under Chronic Neurodegenerative Conditions Triggered by Perinatal Asphyxia [PDF]

open access: yesFrontiers in Pharmacology, 2018
Perinatal asphyxia (PA) remains as one of the most important causes of short-term mortality, psychiatric and neurological disorders in children, without an effective treatment.
G. Ezequiel Saraceno   +6 more
doaj   +4 more sources

Oligodendrocyte origin and development in the zebrafish visual system

open access: yesJournal of Comparative Neurology, Volume 531, Issue 4, Page 515-527, March 2023., 2023
Graphical Abstract The first oligodendrocyte progenitor cells (OPCs, olig2:EGFP/Sox2, yellow cells) are detected in the preoptical area of the hypothalamus at 2 dpf. One day later, 3 dpf, these cells invade the optic chiasm and colonize the postchiasmatic region first and the prechiasmatic later (yellow cells). As they differentiate to oligodendrocytes,
Adrián Santos‐Ledo   +4 more
wiley   +1 more source

The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia

open access: yesAlzheimer's &Dementia, Volume 18, Issue 4, Page 654-675, April 2022., 2022
Abstract Introduction Diet and exercise influence the risk of cognitive decline (CD) and dementia through the food metabolome and exercise‐triggered endogenous factors, which use the blood as a vehicle to communicate with the brain. These factors might act in concert with hippocampal neurogenesis (HN) to shape CD and dementia. Methods Using an in vitro
Andrea Du Preez   +21 more
wiley   +1 more source

Kainate receptor modulation of glutamatergic synaptic transmission in the CA2 region of the hippocampus

open access: yesJournal of Neurochemistry, Volume 158, Issue 5, Page 1083-1093, September 2021., 2021
Kainate receptors (KARs) located in hippocampal CA3 neurons contacting CA2 pyramidal cells mediate a decrease in glutamate release. This depression of glutamate release requires Gi/o protein and protein kinase A (PKA) signaling. This is the first time KARs have been described in the CA2 region of the hippocampus.
Rafael Falcón‐Moya   +2 more
wiley   +1 more source

Impaired Cerebral Vasomotor Reactivity in Alzheimer's Disease. [PDF]

open access: yesInt J Alzheimers Dis, 2018
Background. Recent studies have shown that cerebral vascularity may be impaired in Alzheimer’s disease. Cerebral vasomotor reactivity could be an important biomarker for this pathology. Aims. The aim of this study was to investigate the alterations in cerebral vascular motor reactivity in Alzheimer’s disease subjects and to associate these changes with
Gongora-Rivera F   +7 more
europepmc   +2 more sources

Integrated Stress Response as a Therapeutic Target for CNS Injuries. [PDF]

open access: yesBiomed Res Int, 2017
Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or mechanical contusions (e.g., traumatic brain injury, TBI) comprise a diverse group of disorders that share the activation of the integrated stress response (ISR). This pathway is an innate protective mechanism, with encouraging potential as therapeutic target for CNS injury
Romero-Ramírez L   +2 more
europepmc   +2 more sources

Morphometric evidences for regional variation in potential of neural plasticity [PDF]

open access: yes, 2006
The neural plasticity showing the ability of nervous system to change its structure and function is a well-documented fact. However regional variation within a CNS structure to undergo plastic changes has been shown by limited studies.
Behnampour, N.   +3 more
core   +1 more source

Corporeidade, Movimento, Plasticidade Neuronal e Maturidade Ativa

open access: yesEstudos Interdisciplinares sobre o Envelhecimento, 2001
Resumo: Nos dias de hoje existe uma perda das referências do indivíduo como alguém possuidor de qualidades únicas. A padronização de gestos e condutas faz com que muitos não reconheçam suas sensações como legítimas buscando-se adequar a um modelo dos Meios de Comunicação Social (MCS).
Gonçalves, Clézio J. S.   +1 more
openaire   +4 more sources

Evidencias y perspectivas del potencial antidepresivo del “alcaloide mágico” psilocibina: una revisión narrativa

open access: yesCultura y Droga, 2023
La psilocibina es un alcaloide psicodélico producido naturalmente por diversas especies de hongos, especialmente del género Psilocybe, cuyo uso por parte de culturas precolombinas ha sido ampliamente documentado.
María Marcela Velásquez Toledo
doaj   +1 more source

Programming of Dopaminergic Neurons by Neonatal Sex Hormone Exposure: Effects on Dopamine Content and Tyrosine Hydroxylase Expression in Adult Male Rats

open access: yesNeural Plasticity, Volume 2016, Issue 1, 2016., 2016
We sought to determine the long‐term changes produced by neonatal sex hormone administration on the functioning of midbrain dopaminergic neurons in adult male rats. Sprague‐Dawley rats were injected subcutaneously at postnatal day 1 and were assigned to the following experimental groups: TP (testosterone propionate of 1.0 mg/50 μL); DHT ...
Pedro Espinosa   +10 more
wiley   +1 more source

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