Results 11 to 20 of about 11,777 (212)

Hippocampal Dendritic Spines Modifications Induced by Perinatal Asphyxia

Neural Plasticity, 2012
Perinatal asphyxia (PA) affects the synaptic function and morphological organization. In previous works, we have shown neuronal and synaptic changes in rat neostriatum subjected to hypoxia leading to long-term ubi-protein accumulation.
G. E. Saraceno, R. Castilla, G. E. Barreto, J. Gonzalez, R. A. Kölliker-Frers, F. Capani   +5 more
doaj   +2 more sources

Oligodendrocyte origin and development in the zebrafish visual system

Journal of Comparative Neurology, Volume 531, Issue 4, Page 515-527, March 2023., 2023
Graphical Abstract The first oligodendrocyte progenitor cells (OPCs, olig2:EGFP/Sox2, yellow cells) are detected in the preoptical area of the hypothalamus at 2 dpf. One day later, 3 dpf, these cells invade the optic chiasm and colonize the postchiasmatic region first and the prechiasmatic later (yellow cells). As they differentiate to oligodendrocytes,
Adrián Santos‐Ledo, Cristina Pérez‐Montes, Laura DeOliveira‐Mello, Rosario Arévalo, Almudena Velasco   +4 more
wiley   +1 more source

The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia

Alzheimer's &Dementia, Volume 18, Issue 4, Page 654-675, April 2022., 2022
Abstract Introduction Diet and exercise influence the risk of cognitive decline (CD) and dementia through the food metabolome and exercise‐triggered endogenous factors, which use the blood as a vehicle to communicate with the brain. These factors might act in concert with hippocampal neurogenesis (HN) to shape CD and dementia. Methods Using an in vitro
Andrea Du Preez, Sophie Lefèvre‐Arbogast, Vikki Houghton, Chiara de Lucia, Dorrain Y. Low, Catherine Helmer, Catherine Féart, Cécile Delcourt, Cécile Proust‐Lima, Mercè Pallàs, Silvie R. Ruigrok, Barbara Altendorfer, Raúl González‐Domínguez, Alex Sánchez‐Pla, Mireia Urpi‐Sardà, Cristina Andres‐Lacueva, Ludwig Aigner, Paul J. Lucassen, Aniko Korosi, Claudine Manach, Cécilia Samieri, Sandrine Thuret   +21 more
wiley   +1 more source

Kainate receptor modulation of glutamatergic synaptic transmission in the CA2 region of the hippocampus

Journal of Neurochemistry, Volume 158, Issue 5, Page 1083-1093, September 2021., 2021
Kainate receptors (KARs) located in hippocampal CA3 neurons contacting CA2 pyramidal cells mediate a decrease in glutamate release. This depression of glutamate release requires Gi/o protein and protein kinase A (PKA) signaling. This is the first time KARs have been described in the CA2 region of the hippocampus.
Rafael Falcón‐Moya, Irene Martínez‐Gallego, Antonio Rodríguez‐Moreno   +2 more
wiley   +1 more source

Impaired Cerebral Vasomotor Reactivity in Alzheimer's Disease. [PDF]

Int J Alzheimers Dis, 2018
Background. Recent studies have shown that cerebral vascularity may be impaired in Alzheimer’s disease. Cerebral vasomotor reactivity could be an important biomarker for this pathology. Aims. The aim of this study was to investigate the alterations in cerebral vascular motor reactivity in Alzheimer’s disease subjects and to associate these changes with
Gongora-Rivera F, Cordero-Perez A, Gonzalez-Aquines A, Anaya-Escamilla A, Villarreal-Garza E, Espinosa-Ortega M, Salinas-Carmona MC, Ortiz-Jimenez X.   +7 more
europepmc   +2 more sources

Integrated Stress Response as a Therapeutic Target for CNS Injuries. [PDF]

Biomed Res Int, 2017
Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or mechanical contusions (e.g., traumatic brain injury, TBI) comprise a diverse group of disorders that share the activation of the integrated stress response (ISR). This pathway is an innate protective mechanism, with encouraging potential as therapeutic target for CNS injury
Romero-Ramírez L, Nieto-Sampedro M, Barreda-Manso MA.   +2 more
europepmc   +2 more sources

Morphometric evidences for regional variation in potential of neural plasticity [PDF]

, 2006
The neural plasticity showing the ability of nervous system to change its structure and function is a well-documented fact. However regional variation within a CNS structure to undergo plastic changes has been shown by limited studies.
Behnampour, N., Davarian, A., Fazeli, S.A., Golalipour, M.J.   +3 more
core   +1 more source

High Plasticity of New Granule Cells in the Aging Hippocampus

Cell Reports, 2017
Summary: During aging, the brain undergoes changes that impair cognitive capacity and circuit plasticity, including a marked decrease in production of adult-born hippocampal neurons.
Mariela F. Trinchero, Karina A. Buttner, Jessica N. Sulkes Cuevas, Silvio G. Temprana, Paula A. Fontanet, M. Cristina Monzón-Salinas, Fernanda Ledda, Gustavo Paratcha, Alejandro F. Schinder   +8 more
doaj   +1 more source

αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson’s disease [PDF]

, 2017
The etiology of Parkinson’s disease (PD) converges on a common pathogenic pathway of mitochondrial defects in which α-Synuclein (αSyn) is thought to play a role.
Alloatti, Matías, Cromberg, Lucas Eneas, Dimopoulos, Nicolás, Falzone, Tomas Luis, Marin Burgin, Antonia, Otero, Maria Gabriela, Pardi, María Belén, Pozo Devoto, Victorio Martin, Saez, Trinidad María de Los Milagros, Scassa, Maria Elida, Schinder, Alejandro Fabián, Sevlever, Gustavo, Stokin, Gorazd B.   +12 more
core   +1 more source

SISTEMAS DE INTERFAZ NEURONAL Y SU DESARROLLO EN LAS NEUROCIENCIAS: REVISIÓN BIBLIOGRÁFICA SISTEMÁTICA ACERCA DE SU APLICACIÓN EN PERSONAS CON PARÁLISIS

Ciencias Psicológicas, 2014
El presente artículo tiene como objetivo sistematizar la evidencia de estudios de la última década sobre la aplicación de sistemas de interfaces neuronales en humanos con parálisis.
Boris Lucero M., María Teresa Muñoz-Quezada   +1 more
doaj   +1 more source