Results 11 to 20 of about 1,418,382 (391)
Summary 1The role of phenotypic plasticity in evolution has historically been a contentious issue because of debate over whether plasticity shields genotypes from selection or generates novel opportunities for selection to act.
John K Mckay, Zan‐yang Xing
exaly +2 more sources
Top-down inputs enhance orientation selectivity in neurons of the primary visual cortex during perceptual learning. [PDF]
Perceptual learning has been used to probe the mechanisms of cortical plasticity in the adult brain. Feedback projections are ubiquitous in the cortex, but little is known about their role in cortical plasticity.
Bazhenov, Maxim+2 more
core +16 more sources
Effect of competitive cues on reproductive morphology and behavioral plasticity in male fruitflies [PDF]
Phenotypic plasticity will be favored whenever there are significant fitness benefits of responding to environmental variation. The extent and nature of the plasticity that evolves depends on the rate of environmental fluctuations and the capacity to ...
Bretman, Amanda+3 more
core +4 more sources
Tumor cell plasticity in targeted therapy-induced resistance: mechanisms and new strategies
Despite the success of targeted therapies in cancer treatment, therapy-induced resistance remains a major obstacle to a complete cure. Tumor cells evade treatments and relapse via phenotypic switching driven by intrinsic or induced cell plasticity ...
Zhenjun Shi+8 more
semanticscholar +1 more source
Online conversion of reconstructed neural morphologies into standardized SWC format
Digital reconstructions provide an accurate and reliable way to store, share, model, quantify, and analyze neural morphology. Continuous advances in cellular labeling, tissue processing, microscopic imaging, and automated tracing catalyzed a ...
Ketan Mehta+6 more
doaj +1 more source
Plasticity, plasticity, plasticity…and the rigid problem of sex [PDF]
Why is popular understanding of female–male differences still based on rigid models of development, even though contemporary developmental sciences emphasize plasticity? Is it because the science of sex differences still works from the same rigid models?
Fine, Cordelia+3 more
openaire +4 more sources
Background The Bergen 4-day treatment (B4DT) is a concentrated exposure-based therapy that has been shown to be effective in the treatment of anxiety disorders.
Kay Morten Hjelle+7 more
doaj +1 more source
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling
Drug resistance in cancer is often linked to changes in tumor cell state or lineage, but the molecular mechanisms driving this plasticity remain unclear. Using murine organoid and genetically engineered mouse models, we investigated the causes of lineage
J. Chan+26 more
semanticscholar +1 more source
Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan+4 more
doaj +1 more source
Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable.
Andrea Giorni+5 more
doaj +1 more source