Results 41 to 50 of about 491,145 (268)
Long-term follow-up of the Bergen 4-day treatment for panic disorder during the COVID-19 pandemic
Cogent PsychologyThe COVID-19 pandemic has necessitated essential modifications to the administration of psychotherapy for patients with panic disorder (PD) through the increased use of videoconferencing.
Kay Morten Hjelle +7 more
doaj +1 more source
Clusters of synaptic inputs on dendrites of layer 5 pyramidal cells in mouse visual cortex
eLife, 2016 The spatial organization of synaptic inputs on the dendritic tree of cortical neurons plays a major role for dendritic integration and neural computations, yet, remarkably little is known about it.
Onur Gökçe +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
LRP4 is required for the olfactory association task in the piriform cortex
Cell & Bioscience, 2022 Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan +12 more
doaj +1 more source
Rehabilitation and Plasticity [PDF]
, 2013 Therapies for effective neurorehabiltiation are in part based on brain mechanism commonly described as neuroplasticity. These therapeutic approaches emphasize the re-learning of functionality that was lost due to the injury through reorganization of neural circuits in the remaining intact tissue.
openaire +3 more sources
New plastic joints for plastic orthoses [PDF]
Prosthetics & Orthotics International, 1982 Plastic joints for orthoses have more advantages than metal joints. They are lightweight, noiseless comfortable to use, rust proof, corrosion free, and radiolucent. Two types of plastic joints were developed by the authors, one for the ankle joint and the other for the knee joint, elbow joint or hip joint. Polypropylene was chosen as the joint material
H, Watanabe +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Mobile DNABackground Glioblastoma, the most common primary malignant brain tumor, has a median survival of less than two years. This is due in part to a subpopulation of cells called glioblastoma stem cells (GSCs), which drive tumor recurrence.
Mattia D. Pizzagalli +3 more
doaj +1 more source
Alzheimer’s Research & Therapy, 2018 Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with a high prevalence among the elderly and a huge personal and societal impact.
Sylvie L. Lesuis +7 more
doaj +1 more source