Results 21 to 30 of about 1,166,563 (204)
Essential plasticity and redundancy of metabolism unveiled by synthetic lethality analysis
, 2014 We unravel how functional plasticity and redundancy are essential mechanisms underlying the ability to survive of metabolic networks. We perform an exhaustive computational screening of synthetic lethal reaction pairs in Escherichia coli in a minimal ...
Güell, Oriol +2 more
core +6 more sources
GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors
iScience, 2023 Summary: Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored.
Jithin D. Nair +6 more
doaj +1 more source
Fluctuating population dynamics promotes the evolution of phenotypic plasticity [PDF]
, 2007 An increasing number of studies are showing evidence in support of sympatric speciation. One basic question remains, however. When a population has undergone a branching in its phenotype, is this due to an evolutionary branching in the underlying ...
Mario Pineda-Krch +2 more
core +2 more sources
Journal of Neuroinflammation, 2020 Background Early-life stress (ES) is an emerging risk factor for later life development of Alzheimer’s disease (AD). We have previously shown that ES modulates amyloid-beta pathology and the microglial response to it in the APPswe/PS1dE9 mouse model ...
Maralinde R. Abbink +7 more
doaj +1 more source
Whole-brain tracking of cocaine and sugar rewards processing
Translational Psychiatry, 2023 Natural rewards, such as food, and sex are appetitive stimuli available for animals in their natural environment. Similarly, addictive rewards such as drugs of abuse possess strong, positive valence, but their action relies on their pharmacological ...
Łukasz Bijoch +7 more
doaj +1 more source
, 2018 Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity.
Gallinaro, Júlia V, Rotter, Stefan
core +2 more sources
Tool use induces complex and flexible plasticity of human body representations [PDF]
, 2012 Plasticity of body representation fundamentally underpins human tool use. Recent studies have demonstrated remarkably complex plasticity of body representation in humans, showing that such plasticity: (1) occurs flexibly across multiple time-scales, and (
Longo, Matthew R., Serino, A.
core +1 more source
Critical neural networks with short and long term plasticity
, 2017 In recent years self organised critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behaviour of neuronal systems.
de Arcangelis, L. +3 more
core +3 more sources
Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth
eLife, 2014 Endocannabinoids are recently recognized regulators of brain development, but molecular effectors downstream of type-1 cannabinoid receptor (CB1R)-activation remain incompletely understood.
Alexandre B Roland +10 more
doaj +1 more source