Results 11 to 20 of about 470,234 (268)
Sensory plasticity in a socially plastic bee [PDF]
Journal of Evolutionary Biology, 2022 Abstract The social Hymenoptera have contributed much to our understanding of the evolution of sensory systems. Attention has focussed chiefly on how sociality and sensory systems have evolved together. In the Hymenoptera, the antennal sensilla are important for optimizing the perception of olfactory social ...
Boulton, Rebecca A., Field, Jeremy
openaire +5 more sources
Whole-brain tracking of cocaine and sugar rewards processing
Translational Psychiatry, 2023 Natural rewards, such as food, and sex are appetitive stimuli available for animals in their natural environment. Similarly, addictive rewards such as drugs of abuse possess strong, positive valence, but their action relies on their pharmacological ...
Łukasz Bijoch +7 more
doaj +1 more source
Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice
Translational Psychiatry, 2021 Anxiety-like behavior of rodents is frequently accompanied by reduced exploration. Here, we identify dissociable components of anxiety, fear, and exploratory drive of sated and foraging mice.
Daniel E. Heinz +6 more
doaj +1 more source
GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors
iScience, 2023 Summary: Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored.
Jithin D. Nair +6 more
doaj +1 more source
Journal of Neuroinflammation, 2020 Background Early-life stress (ES) is an emerging risk factor for later life development of Alzheimer’s disease (AD). We have previously shown that ES modulates amyloid-beta pathology and the microglial response to it in the APPswe/PS1dE9 mouse model ...
Maralinde R. Abbink +7 more
doaj +1 more source
Post Disaster Rooftops. Ep01 - Taranto 2049 [PDF]
Pad, 2018 Post Disaster Rooftops is a curatorial exercise that uses the architecture of the city as a platform to investigate the marginal condition of the Mediterranean urban scenario.
Gabriele Leo +3 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source