Results 11 to 20 of about 465,947 (169)

Regenerative neurogenic response from glia requires insulin-driven neuron-glia communication

open access: yeseLife, 2021
Understanding how injury to the central nervous system induces de novo neurogenesis in animals would help promote regeneration in humans. Regenerative neurogenesis could originate from glia and glial neuron-glia antigen-2 (NG2) may sense injury-induced ...
Neale J Harrison   +8 more
doaj   +1 more source

Glial Plasticity [PDF]

open access: yesNeural Plasticity, 2015
Editorial
Tomas C. Bellamy   +2 more
openaire   +3 more sources

Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice

open access: yesTranslational Psychiatry, 2021
Anxiety-like behavior of rodents is frequently accompanied by reduced exploration. Here, we identify dissociable components of anxiety, fear, and exploratory drive of sated and foraging mice.
Daniel E. Heinz   +6 more
doaj   +1 more source

Characterization of astrocytes throughout life in wildtype and APP/PS1 mice after early-life stress exposure

open access: yesJournal of Neuroinflammation, 2020
Background Early-life stress (ES) is an emerging risk factor for later life development of Alzheimer’s disease (AD). We have previously shown that ES modulates amyloid-beta pathology and the microglial response to it in the APPswe/PS1dE9 mouse model ...
Maralinde R. Abbink   +7 more
doaj   +1 more source

Whole-brain tracking of cocaine and sugar rewards processing

open access: yesTranslational Psychiatry, 2023
Natural rewards, such as food, and sex are appetitive stimuli available for animals in their natural environment. Similarly, addictive rewards such as drugs of abuse possess strong, positive valence, but their action relies on their pharmacological ...
Łukasz Bijoch   +7 more
doaj   +1 more source

GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors

open access: yesiScience, 2023
Summary: Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored.
Jithin D. Nair   +6 more
doaj   +1 more source

Post Disaster Rooftops. Ep01 - Taranto 2049 [PDF]

open access: yesPad, 2018
Post Disaster Rooftops is a curatorial exercise that uses the architecture of the city as a platform to investigate the marginal condition of the Mediterranean urban scenario.
Gabriele Leo   +3 more
doaj  

Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth

open access: yeseLife, 2014
Endocannabinoids are recently recognized regulators of brain development, but molecular effectors downstream of type-1 cannabinoid receptor (CB1R)-activation remain incompletely understood.
Alexandre B Roland   +10 more
doaj   +1 more source

Ancestral glycoprotein hormone-receptor pathway controls growth in C. elegans

open access: yesFrontiers in Endocrinology, 2023
In vertebrates, thyrostimulin is a highly conserved glycoprotein hormone that, besides thyroid stimulating hormone (TSH), is a potent ligand of the TSH receptor.
Signe Kenis   +6 more
doaj   +1 more source

The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression

open access: yeseLife, 2019
Cannabinoid type one receptor (CB1R) is only stably surface expressed in axons, where it downregulates neurotransmitter release. How this tightly regulated axonal surface polarity is established and maintained is unclear.
Alexandra Fletcher-Jones   +5 more
doaj   +1 more source

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