Results 61 to 70 of about 491,145 (268)

Retracted: Sustained Auditory Attentional Load Decreases Audiovisual Integration in Older and Younger Adults

Neural Plasticity, 2023
Neural Plasticity
doaj   +1 more source

A simplified microwave-based motion detector for home cage activity monitoring in mice

Journal of Biological Engineering, 2017
Background Locomotor activity of rodents is an important readout to assess well-being and physical health, and is pivotal for behavioral phenotyping.
Andreas Genewsky, Daniel E. Heinz, Paul M. Kaplick, Kasyoka Kilonzo, Carsten T. Wotjak   +4 more
doaj   +1 more source

The future is plastic: refiguring Malabou’s plasticity

Journal for Cultural Research, 2014
This article investigates Catherine Malabou’s claims to have produced some form of beyond of deconstruction with her reworking of the Hegelian concept of “plasticity” (Plastizität). In the light of Malabou’s critique of the unsuitability of the Derridean non-concept of “text” for being a suitable metaphor for neuronal functioning in her Plasticité, I ...
openaire   +2 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

LATERODORSAL NUCLEUS OF THE THALAMUS HEAD DIRECTION-TUNED CELLS CONTRIBUTION TO LONG-TERM CONTEXTUAL FEAR MEMORY CONSOLIDATION.

IBRO Neuroscience Reports, 2023
José Casanova, Clément Pouget, Maëlle Christiaens, Gisella Vetere   +3 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Retracted: Three Mediating Pathways of Anxiety and Security in the Relationship between Coping Style and Disordered Eating Behaviors among Chinese Female College Students

Neural Plasticity, 2023
Neural Plasticity
doaj   +1 more source

The effectiveness and acceptability of the Bergen 4-day treatment for adolescents with OCD: a replication and extension

BMC Psychiatry
Background B4DT is a concentrated treatment format with prolonged sessions of exposure and ritual prevention (ERP) delivered over four consecutive days.
Solvei Harila Skjold, Kristen Hagen, Michael G. Wheaton, Kay Morten Hjelle, Thröstur Björgvinsson, Bjarne Hansen   +5 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source