Results 61 to 70 of about 530,147 (296)

LATERODORSAL NUCLEUS OF THE THALAMUS HEAD DIRECTION-TUNED CELLS CONTRIBUTION TO LONG-TERM CONTEXTUAL FEAR MEMORY CONSOLIDATION.

IBRO Neuroscience Reports, 2023
José Casanova, Clément Pouget, Maëlle Christiaens, Gisella Vetere   +3 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Retracted: Sports Augmented Cognitive Benefits: An fMRI Study of Executive Function with Go/NoGo Task

Neural Plasticity, 2023
Neural Plasticity
doaj   +1 more source

NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor

Scientific Reports, 2018
NCAM1 and NCAM2 have ectodomains consisting of 5 Ig domains followed by 2 membrane-proximal FnIII domains. In this study we investigate and compare the structures and functions of these FnIII domains. The NCAM1 and -2 FnIII2 domains both contain a Walker
Kim Krighaar Rasmussen, Maria Hansen Falkesgaard, Malene Winther, Nikolaj Kulahin Roed, Christine Louise Quistgaard, Marie Nygaard Teisen, Sofie Marie Edslev, David Leander Petersen, Ali Aljubouri, Claus Christensen, Peter Waaben Thulstrup, Leila Lo Leggio, Kaare Teilum, Peter Schledermann Walmod   +13 more
doaj   +1 more source

Supplementary Figure 2 from Stromal EGF and IGF-I Together Modulate Plasticity of Disseminated Triple-Negative Breast Tumors

, 2023
Zafira Castaño, Timothy Marsh, Ramya Tadipatri, Hanna S. Kuznetsov, Fátima Al‐Shahrour, Mahnaz Paktinat, April Greene-Colozzi, Björn Nilsson, Andrea L. Richardson, Sandra S. McAllister   +9 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Improved Acuity and Dexterity but Unchanged Touch and Pain Thresholds following Repetitive Sensory Stimulation of the Fingers

Neural Plasticity, 2012
Neuroplasticity underlies the brain’s ability to alter perception and behavior through training, practice, or simply exposure to sensory stimulation.
Rebecca Kowalewski, Jan-Christoph Kattenstroth, Tobias Kalisch, Hubert R. Dinse   +3 more
doaj   +1 more source

Diversified glucosinolate metabolism: biosynthesis of hydrogen cyanide and of the hydroxynitrile glucoside alliarinoside in relation to sinigrin metabolism in Alliaria petiolata

Frontiers in Plant Science, 2015
Alliaria petiolata (garlic mustard, Brassicaceae) contains the glucosinolate sinigrin as well as alliarinoside, a γ-hydroxynitrile glucoside structurally related to cyanogenic glucosides.
Tina eFrisch, Tina eFrisch, Mohammed Saddik Motawia, Mohammed Saddik Motawia, Mohammed Saddik Motawia, Carl Erik eOlsen, Carl Erik eOlsen, Carl Erik eOlsen, Niels eAgerbirk, Niels eAgerbirk, Birger Lindberg Møller, Birger Lindberg Møller, Birger Lindberg Møller, Birger Lindberg Møller, Nanna eBjarnholt, Nanna eBjarnholt, Nanna eBjarnholt   +16 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

PKCδ is an activator of neuronal mitochondrial metabolism that mediates the spacing effect on memory consolidation

eLife
Relevance-based selectivity and high energy cost are two distinct features of long-term memory (LTM) formation that warrant its default inhibition. Spaced repetition of learning is a highly conserved cognitive mechanism that can lift this inhibition ...
Typhaine Comyn, Thomas Preat, Alice Pavlowsky, Pierre-Yves Plaçais   +3 more
doaj   +1 more source