Results 71 to 80 of about 1,298,913 (269)

JNK activation in TA and EDL muscle is load-dependent in rats receiving identical excitation patterns

open access: yesScientific Reports, 2021
As the excitation–contraction coupling is inseparable during voluntary exercise, the relative contribution of the mechanical and neural input on hypertrophy-related molecular signalling is still poorly understood.
Einar Eftestøl   +3 more
doaj   +1 more source

Targeting CNS Neural Mechanisms of Gait in Stroke Neurorehabilitation

open access: yesBrain Sciences, 2022
The central nervous system (CNS) control of human gait is complex, including descending cortical control, affective ascending neural pathways, interhemispheric communication, whole brain networks of functional connectivity, and neural interactions ...
Jessica P. McCabe   +2 more
doaj   +1 more source

Foraging environment determines the genetic architecture and evolutionary potential of trophic morphology in cichlid fishes [PDF]

open access: yes, 2016
Phenotypic plasticity allows organisms to change their phenotype in response to shifts in the environment. While a central topic in current discussions of evolutionary potential, a comprehensive understanding of the genetic underpinnings of plasticity is
Albertson, R. Craig   +7 more
core   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Insomnia as a predictor of treatment outcomes in adolescents receiving concentrated exposure treatment for OCD

open access: yesBMC Psychiatry
Background Research suggests that individuals with obsessive-compulsive disorder (OCD) frequently experience insomnia. Some previous studies have suggested that insomnia may predict treatment outcomes, but the evidence is limited, especially for ...
Solvei Harila Skjold   +6 more
doaj   +1 more source

Diffuse-interface polycrystal plasticity: Expressing grain boundaries as geometrically necessary dislocations

open access: yes, 2017
The standard way of modeling plasticity in polycrystals is by using the crystal plasticity model for single crystals in each grain, and imposing suitable traction and slip boundary conditions across grain boundaries.
Admal, Nikhil Chandra   +2 more
core   +1 more source

Beyond buying time: the role of plasticity in phenotypic adaptation to rapid environmental change

open access: yesPhilosophical Transactions of the Royal Society of London. Biological Sciences, 2019
How populations and species respond to modified environmental conditions is critical to their persistence both now and into the future, particularly given the increasing pace of environmental change.
R. Fox   +4 more
semanticscholar   +1 more source

A Plastic Clock [PDF]

open access: yesNeuron, 2013
Although circadian clocks normally run with a 24 hr period, Brancaccio et al. (2013) report in this issue of Neuron that transiently activating G protein signaling can lengthen period even after the stimulus is removed, revealing an unexpected plasticity in the central brain clock.
Ben Collins, Justin Blau
openaire   +3 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Deep learning predicts path-dependent plasticity

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance We show that material plasticity can be precisely and efficiently predicted by deep-learning methods. This approach is fundamentally different from the century-old theory of continuum plasticity because it is not iteratively tracing the ...
M. Mozaffar   +6 more
semanticscholar   +1 more source

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