Results 31 to 40 of about 118,485 (254)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Yantu gongcheng xuebao, 2017 Using the ring shear apparatus, the variation rules of residual strength of 17 saturated claysoil samples with different plasticity indices under different consolidation conditions are studied.
XU Cheng-shun , WANG Xin , DU Xiu-li , DAI Fu-chu , WANG Guo-sheng , GAO Yan
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
工程科学与技术, 2018 The shear strength of expansive soil is not only influenced by the water content, dry density, vertical stress, wetting-drying cycle, crack and other factors, but also influenced by the clay content and plasticity index.
Fuchu DAI +5 more
doaj
Plasticity role in strength behavior of cement-phosphogypsum stabilized soils
Journal of Rock Mechanics and Geotechnical Engineering, 2022 Dredged soil and phosphogypsum are frequently regarded as wasted materials, which require further treatment to control their environmental impact. Hence, phosphogypsum is proposed as a binder to stabilize dredged soil, aiming at efficiently reducing and ...
Xia Bian +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Improvement expansive soil properties (l.l, p.l, p.i) using ordinary Portland cement
Al-Qadisiyah Journal for Engineering Science, 2015 The idea of this research is to improve the properties of expansive soil, such as, liquid limit, plastic limit and shrinkage limit by adding different amount of Ordinary Portland Cement to expansive soil.
Saba. M. Shaheed
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Efficient Swell Risk Prediction for Building Design Using a Domain-Guided Machine Learning Model
BuildingsExpansive clays damage the foundations, slabs, and utilities of low- and mid-rise buildings, threatening daily operations and incurring billions of dollars in costs globally.
Hani S. Alharbi
doaj +1 more source