Results 41 to 50 of about 116,428 (287)

Pupillometry indexes ocular dominance plasticity

Vision Research
Short-term monocular deprivation in normally sighted adult humans produces a transient shift of ocular dominance, boosting the deprived eye. This effect has been documented with both perceptual tests and through physiological recordings, but no previous study simultaneously measured physiological responses and the perceptual effects of deprivation ...
Acquafredda M., Binda P.
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Thermally Treated Clay as a Stabilizing Agent for Expansive Clayey Soil: Some Engineering Properties

Studia Geotechnica et Mechanica, 2018
The objective of this research was to investigate the effect of adding thermally treated clay on some engineering properties of the untreated expansive clayey soil.
Al-Swaidani Aref M., Hamood Ibraheem, Meziab Ayman   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Use of fall-cone flow index for soil classification:a new plasticity chart [PDF]

, 2022
Use of the Casagrande-style plasticity chart to classify fine-grained soils using Atterberg’s liquid and plastic limits is ubiquitous in geotechnical engineering.
Vardanega, Paul J., Zhang, Xianwei, Brendan C. O'Kelly, O'Kelly, Brendan C., Paul J. Vardanega, Wang, Gang, O’Kelly, Brendan C., Stuart K. Haigh, Liu, Xinyu, Chen, Cheng, Xinyu Liu, Gang Wang, Cheng Chen, Haigh, Stuart K., Xianwei Zhang   +14 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Study on Shear Strength of Undisturbed Expansive Soil of Middle Route of South-to-North Water Diversion Project

工程科学与技术, 2018
The shear strength of expansive soil is not only influenced by the water content, dry density, vertical stress, wetting-drying cycle, crack and other factors, but also influenced by the clay content and plasticity index.
Fuchu DAI, Wenping DONG, Zhiquan HUANG, Xiaoli ZHANG, Anming WANG, Shichao CAO   +5 more
doaj  

COMPARATIVE ANALYSIS OF ATTERBERG’S LIMITS OF FINE-GRAINED SOIL DETERMINED BY VARIOUS METHODS

Facta Universitatis. Series: Architecture and Civil Engineering
Determination of the Atterberg’s limits is necessary for the classification of fine-grained soil. That limits can be determined according to the valid standard SRPS EN ISO 17892-12.
Nemanja Marinković, Elefterija Zlatanović, Nebojša Davidović, Zoran Bonić, Nikola Romić, Branimir Stanković, Lazar Živković   +6 more
doaj   +1 more source