Results 51 to 60 of about 118,485 (254)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Effect of Light Intensity on the Functional Traits of Two Ormosia Species
AgronomyThis study investigated two Ormosia species, Ormosia henryi and Ormosia hosiei, to examine their adaptive mechanisms to varying light conditions.
Guohua He +7 more
doaj +1 more source
Thermally Treated Clay as a Stabilizing Agent for Expansive Clayey Soil: Some Engineering Properties
Studia Geotechnica et Mechanica, 2018 The objective of this research was to investigate the effect of adding thermally treated clay on some engineering properties of the untreated expansive clayey soil.
Al-Swaidani Aref M. +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Experimental study on undrained thixotropic cyclic resistance characteristics of marine soft clay
Yantu gongcheng xuebaoA series of unconsolidated undrained cyclic triaxial tests are carried out on the marine soft clay in the estuary of Yangtze River. The effects of age T, water content w and plasticity index IP on the thixotropic cyclic resistance of the remolded marine ...
WU Qi 1, JI Dongwei 1, XIAO Xing 1, ZHU Shengdong 1, 2, CHEN Guoxing 1
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
EVALUATION OF GEOTECHNICAL PROPERTIES OF SOILS AT BRITISH – AMERICAN AREA, JOS-PLATEAU, NORTHCENTRAL NIGERIA [PDF]
Journal CleanWASThis research aimed to determine the geotechnical properties of soils along the British American area, Jos, Northcentral Nigeria. A total of five (5) soil samples were collected at a depth of 1.5 m and subjected to geotechnical tests: moisture content ...
Shola C. Odewumi
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
COMPARATIVE ANALYSIS OF ATTERBERG’S LIMITS OF FINE-GRAINED SOIL DETERMINED BY VARIOUS METHODS
Facta Universitatis. Series: Architecture and Civil EngineeringDetermination of the Atterberg’s limits is necessary for the classification of fine-grained soil. That limits can be determined according to the valid standard SRPS EN ISO 17892-12.
Nemanja Marinković +6 more
doaj +1 more source