Results 51 to 60 of about 116,428 (287)

Nanoindentation characterization of polymer nanocomposites for elastic and viscoelastic properties: Experimental and mathematical approach

open access: yesComposites Part C: Open Access, 2021
This work aims to determine the elastic and viscoelastic properties of microwave processed nanocomposites. Three different power rating has been used in microwave processing of polymer nanocomposite, i.e., 180 W, 360 W, and 540 W.
Gaurav Arora, Himanshu Pathak
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

KOEFISIEN GESEK TANAH KELEMPUNGAN BERDASARKAN INDEX PLASTISITASNYA

open access: yesCivil Engineering Dimension, 2004
The plasticity index of clayey soils has been known as a good indicator for many soil parameters. This paper describes how the plasticity index of clays correlates well with the friction coefficient on certain concrete interfaces.
Johanes Suwono
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Plasticidade morfoanatômica foliar de Tibouchina clavata (Melastomataceae) ocorrente em duas formações de restinga

open access: yesRodriguésia
Resumo Respostas plásticas em plantas podem ser induzidas pela heterogeneidade espacial, sendo a restinga um ecossistema favorável á compreensão dessas respostas em função das condições ambientais limitantes que apresenta.
Maick Willian Amorim   +1 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Effect of Soft Nanoparticle Size and Concentration on Wear Behavior in Mixed Lubrication Conditions

open access: yesTribology Online
This research study investigates how incorporating soft nanoparticles affect the wear behavior and the characteristics of the materials in three-body mixed lubrication conditions.
Yunn-Lin Hwang, Adhitya, Jeng-Haur Horng
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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