Results 51 to 60 of about 9,105 (323)

A fatigue crack initiation model incorporating discrete dislocation plasticity and surface roughness [PDF]

, 2007
Although a thorough understanding of fatigue crack initiation is lacking, experiments have shown that the evolution of distinct dislocation distributions and surface roughness are key ingredients.
Brinckmann, Steffen, Van der Giessen, Erik   +1 more
core   +4 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Low velocity impact modeling in composite laminates capturing permanent indentation [PDF]

, 2012
This paper deals with impact damage and permanent indentation modeling. A numerical model has been elaborated in order to simulate the different impact damage types developing during low velocity/low energy impact.
Barrau, Jean-Jacques, Bouvet, Christophe, Rivallant, Samuel   +2 more
core   +4 more sources

Numerical Modelling of Roughness and Plasticity Induced Crack Closure Effects in Fatigue [PDF]

Materials Science Forum, 2000
The incidence of roughness induced fatigue crack closure has been studied by finite element modelling. Closure analyses in the literature have been reviewed and been shown to lack a reasonable treatment of: (a) propagating elastic-plastic cracks, and (b) the influence of the characteristically inhomogeneous plastic deformation associated with near ...
Parry, M.R., Syngellakis, S., Sinclair, I.   +2 more
openaire   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Short fatigue crack growth in welded joints described by the effective cyclic J-integral

MATEC Web of Conferences, 2018
The purpose of the present contribution is to predict the fatigue life of welded joints by using the effective cyclic J-integral as crack driving force.
Tchoffo Ngoula Désiré, Vormwald Michael   +1 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Partial crack closure under block loading [PDF]

, 1980
Fatigue crack propagation tests under high-low and low-high block loading sequences have been performed in aluminium alloy specimens. The tests were carried out at constant [Delta]K conditions. Two stress ratios were analysed: R = 0.05 and R = 0.4. Crack
Borrego, L. P., Ferreira, J. M., Costa, J. M.   +2 more
core   +2 more sources

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source