Results 101 to 110 of about 770,781 (351)
International Journal of Environmental Research and Public Health, 2020 Plasticizers are added to diverse consumer products including children’s products. Owing to their potential for endocrine disruption, the use of phthalate plasticizers is restricted in many children’s products.
Du Yung Kim +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Surface Emissions Modulate Indoor SVOC Concentrations through Volatility-Dependent Partitioning. [PDF]
, 2020 Measurements by semivolatile thermal desorption aerosol gas chromatography (SV-TAG) were used to investigate how semivolatile organic compounds (SVOCs) partition among indoor reservoirs in (1) a manufactured test house under controlled conditions ...
Arata, Caleb +12 more
core
Effect of catalytic conditions on the synthesis of new aconitate esters [PDF]
, 2011 Sugar cane is a crop which generates large amounts of biomass and a juice rich in highvalue natural molecules. After extracting sugar from the juice, the recovering of various compounds such as organic acids contained in molasses could contribute to ...
Hoareau, William +4 more
core +3 more sources
Influence of Bio-Based Plasticizers on the Properties of NBR Materials
Materials, 2020 A high number of technical elastomer products contain plasticizers for tailoring material properties. Some additives used as plasticizers pose a health risk or have inadequate material properties.
M. Rahman +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Вестник СибАДИ, 2019 Introduction. The creation of energy-saving materials involves the use of local raw materials for products with improved physic-mechanical properties. The author carries optimization of the rational composition and properties of modified arbolite from ...
A. K. Matyeva
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Optimization of a PVC Membrane for Reference Field Effect Transistors
Sensors, 2009 For the miniaturization of ISFET sensing systems,the concept of a REFET with low ion sensitivity is proposed to replace the conventional reference electrodes through the arrangement of a quasi reference electrode and a differential readout circuit.
Dorota G. Pijanowska +4 more
doaj +1 more source