Results 81 to 90 of about 770,781 (351)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Differential associations between synthetic endocrine disruptors and renal function impairment across varying degrees in middle-aged and older adult populations

open access: yesFrontiers in Public Health
BackgroundExisting research has revealed that various factors, including environmental pollutants, can affect renal function. This study aims to explore the association between various synthetic Endocrine Disruptors(EDs), which are widely present in the ...
Junfang Mu   +10 more
doaj   +1 more source

Nitramine propellants [PDF]

open access: yes, 1978
Nitramine propellants without a pressure exponent shift in the burning rate curves are prepared by matching the burning rate of a selected nitramine or combination of nitramines within 10% of burning rate of a plasticized active binder so as to smooth ...
Cohen, N. S., Strand, L. D.
core   +1 more source

Organophosphate esters in indoor dust from 12 countries: Concentrations, composition profiles, and human exposure [PDF]

open access: yes, 2019
A total of 20 organophosphate triesters (OPEs), including seven alkyl-OPEs, three chlorinated (Cl)-OPEs, seven aryl-OPEs, and three oligomeric-OPEs were measured in 341 house dust samples collected from 12 countries during the period 2010-2014. OPEs were
문효방
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

FTIR spectroscopic and thermogravimetric characterization of ground tyre rubber devulcanized by microwave treatment [PDF]

open access: yes, 2016
In this work the phenomena involved with the microwave devulcanization of ground tyre rubber (GTR) were investigated. During studies three types of GTR characterized by different content of organic compounds (elastomers, plasticizers, etc..), carbon ...
Bin Musidin, Anwar Faliq   +3 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

High performance ammonium nitrate propellant [PDF]

open access: yes, 1979
A high performance propellant having greatly reduced hydrogen chloride emission is presented. It is comprised of: (1) a minor amount of hydrocarbon binder (10-15%), (2) at least 85% solids including ammonium nitrate as the primary oxidizer (about 40% to ...
Anderson, F. A.
core   +1 more source

Numerical modelling of the filling of formworks with self-compacting concrete [PDF]

open access: yes, 2010
This paper describes the numerical modelling of the flow of self-compacting concrete (SCC) in column and wall formworks during the filling process. It is subdivided in four main parts.
De Schutter, Geert   +6 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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