Results 51 to 60 of about 108,877 (296)

Interfacial nanocomposite sensors (sQRS) for the core monitoring of polymer composites’ fatigue and damage analysis

open access: yesNanocomposites, 2018
The quick development of the smart factory and prognostic and health management (PHM), in the fields of aeronautic, automotive and green energies, is evidencing a need for sensors able to monitor the behavior of composite materials all along their life ...
Suvam Nag-Chowdhury   +5 more
doaj   +1 more source

Active learning for prediction of tensile properties for material extrusion additive manufacturing

open access: yesScientific Reports, 2023
Machine learning techniques were used to predict tensile properties of material extrusion-based additively manufactured parts made with Technomelt PA 6910, a hot melt adhesive.
Tahamina Nasrin   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

A Plastic Clock [PDF]

open access: yesNeuron, 2013
Although circadian clocks normally run with a 24 hr period, Brancaccio et al. (2013) report in this issue of Neuron that transiently activating G protein signaling can lengthen period even after the stimulus is removed, revealing an unexpected plasticity in the central brain clock.
Ben Collins, Justin Blau
openaire   +3 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Predicting mechanical properties of material extrusion additive manufacturing-fabricated structures with limited information

open access: yesScientific Reports, 2022
Mechanical properties of additively manufactured structures fabricated using material extrusion additive manufacturing are predicted through combining thermal modeling with entanglement theory and molecular dynamics approaches. A one-dimensional model of
Amy M. Peterson, David O. Kazmer
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Mandibular Third Molars and Their Influence on Mandibular Angle Fracture Fixation [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2019
Introduction: Mandibular fractures occur commonly in Singapore and 32% involve the angle. The third molar (M3) predisposes the angle to fracture and is often involved in the fracture site.
Arjunan Kumaran   +4 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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