Results 41 to 50 of about 2,894,789 (313)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Medical Expertise at Yekaterinburg Hospital: Legislation and Practice in 1720s–1750s

open access: yesНаучный диалог
This article examines the process of conducting medical expertise at the Yekaterinburg Hospital during the years 1720 to 1750. It highlights that medical examination was mandated by legislation in cases of early resignation from factory service due to ...
A. Plate
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Dynamic stability of a floating plate and a support structure (Influence of elasticity of a support structure on occurrence conditions of the self-excited vibration)

open access: yesNihon Kikai Gakkai ronbunshu, 2019
This paper presents experiments and an analysis of the self-excited vibration of a floating plate and a support structure. The system in which a floating plate and a support structure vibrate, the elasticity of the support structure influences the ...
Masakazu TAKEDA   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Data Management in Distributed, Federated Research Infrastructures: The Case of EPOS

open access: yesData Science Journal
Data management is a key activity when Open Data stewardship through services complying with the FAIR principles is required, as it happens in many National and European initiatives.
Daniele Bailo   +10 more
doaj   +1 more source

HESS Opinions "Classification of hydrological models for flood management" [PDF]

open access: yesHydrology and Earth System Sciences, 2009
Hydrological models for flood management are components of flood risk management, which is the set of actions to be taken to prevent flood disasters.
E. J. Plate
doaj  

Geological archive of the onset of plate tectonics

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2018
Plate tectonics, involving a globally linked system of lateral motion of rigid surface plates, is a characteristic feature of our planet, but estimates of how long it has been the modus operandi of lithospheric formation and interactions range from the ...
Peter A. Cawood   +5 more
semanticscholar   +1 more source

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