Results 61 to 70 of about 1,457,896 (268)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Novel Approach to the Design of Distributed Dynamic Vibration Absorbers for Plates Subjected to Classical and Elastic Edge Conditions

Journal of Marine Science and Engineering
Plate structures are the main components of offshore platforms and ships in engineering applications. The vibration control of the low-frequency mode of plate structures has always been a meaningful research object in marine science and engineering.
Yuan Du, Yuhang Tang, Chenyu Fan, Yucheng Zou, Zhen Bao, Yong Ma   +5 more
doaj   +1 more source

The Interaction between the Plane Wave and the Plate with Limited Height in Soil [PDF]

Учёные записки Казанского университета: Серия Физико-математические науки, 2017
A solution of the two-dimensional task on interaction between the harmonic wave and the plate with the limited height in soil has been provided. The plate surrounded on both sides with the half-spaces filled with soil medium has been used as a vibro ...
N.A. Lokteva, V.N. Paimushin, D.O. Serdyuk, D.V. Tarlakovskii   +3 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Digital Model of Plan View Pattern Control for Plate Mills Based on Machine Vision and the DBO-RBF Algorithm

Metals
Plan view pattern control (PVPC) is a highly effective means to improve the rectangularization of products and increase the yield of plate mills. By optimizing the parameters of PVPC, the effect of PVPC can be further improved.
Zhijie Jiao, Shiwen Gao, Chujie Liu, Junyi Luo, Zhiqiang Wang, Guanyu Lang, Zhong Zhao, Zhiqiang Wu, Chunyu He   +8 more
doaj   +1 more source

Vibrations of Circular Plates Resting on Elastic Foundation with Elastically Restrained Edge Against Translation

The Journal of Engineering Research, 2018
The present paper deals with exact solutions for the free vibration characteristics of thin circular plates resting on Winkler-type elastic foundation based on the classical plate theory elastically restrained against translation.
L.B. Rao, C.K. Rao
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Comparative study on complications of screws versus plates for comminuted radial head and neck fractures with two or three fragments

Frontiers in Surgery
BackgroundThis retrospective study aimed to compare the efficacy of internal fixation using headless compression screws (HCS) and radial head locking plate (RLP) for comminuted radial head and neck fractures with no more than 3 displaced fragments ...
Yuliang Fu, Yuliang Fu, Yuan Cao, Yuan Cao, Zengzhen Cui, Zengzhen Cui, Liangyu Bai, Liangyu Bai, Xiaoyu Norman Pan, Xiaoyu Norman Pan, Yang Lv, Yang Lv   +11 more
doaj   +1 more source

The Case Examination of Detection of Structural Damages on a Plate using Wavelet Transform [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2020
Sometimes, suddenly or gradually structural or nonstructural damages are created in structure’s members due to natural or unnatural reasons like earthquake or corrosion. One of the methods used from the early in last decade to recognize damage is wavelet
Ali Mohammad Rousta, Peyman Beiranvand, Farzad Akbarinia, Mehdi Hooshmand   +3 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source