Results 61 to 70 of about 3,886,063 (302)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

An analytical investigation of the physical dimensions of natural convection flow on a vertical heated plate [PDF]

open access: yes, 2010
Analytical results of the boundary layer of natural convection air flow on a vertical heated plate are presented for both isothermal and constant heat flux plates.
Alzwayi, A.S., Paul, M.C.
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Tilt table for ergometers and other biomedical devices [PDF]

open access: yes, 1971
Table adjusts to any position between horizontal and vertical. Apparatus includes - floor plate, plate hinged to floor plate, for carrying ergometer, hydraulic cylinder and piston on plate sides, linking them, hydraulic system, positive stops, padded ...
Gause, R. L., Spier, R. A.
core   +1 more source

Controllability of a viscoelastic plate using one boundary control in displacement or bending

open access: yes, 2016
In this paper we consider a viscoelastic plate (linear viscoelasticity of the Maxwell-Boltzmann type) and we compare its controllability properties with the (known) controllability of a purely elastic plate (the control acts on the boundary displacement ...
Aassila M.   +8 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Experimental study of a method of reducing the drag of a circular cylinder by installing a flat plate

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2017
The article describes experimental investigation of a method of reducing the drag of a circular cylinder. We consider installation of a flat plate parallel to the flow before the cylinder.
V. A. Frolov, A. S. Kozlova
doaj   +1 more source

Field fluctuations near a conducting plate and Casimir-Polder forces in the presence of boundary conditions [PDF]

open access: yes, 2006
We consider vacuum fluctuations of the quantum electromagnetic field in the presence of an infinite and perfectly conducting plate. We evaluate how the change of vacuum fluctuations due to the plate modifies the Casimir-Polder potential between two atoms
A. Aspect   +7 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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