Results 91 to 100 of about 871,347 (297)
Sudden bending of cracked laminates [PDF]
A dynamic approximate laminated plate theory is developed with emphasis placed on obtaining effective solution for the crack configuration where the 1/square root of r stress singularity and the condition of plane strain are preserved.
Chen, E. P., Sih, G. C.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Bending and buckling of three-dimensional graphene foam plates
Results in Physics, 2019 Bending and buckling behaviors of three-dimensional graphene foam (3D-GrF) plates are investigated in the framework of the two-variable refined plate theory (TRPT).
Yan Qing Wang, Zhi Yuan Zhang
doaj +1 more source
Nonlinear Finite Element Model for Bending Analysis of Functionally-Graded Porous Circular/Annular Micro-Plates under Thermomechanical Loads Using Quasi-3D Reddy Third-Order Plate Theory. [PDF]
Materials (Basel), 2023 Kim J, Nava E, Rakici S.
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
An Electromechanical Model for Clamped-Edge Bimorph Disk Type Piezoelectric Transformer Utilizing Kirchhoff Thin Plate Theory. [PDF]
Sensors (Basel), 2022 Chen SE, Gunawan H, Wu CC.
europepmc +1 more source
Modeling of composite beams and plates for static and dynamic analysis [PDF]
, 1993 A rigorous theory and the corresponding computational algorithms were developed for through-the-thickness analysis of composite plates. This type of analysis is needed in order to find the elastic stiffness constants of a plate.
Hodges, Dewey H.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Stability of Cracked Plates with Nonlinearly Variable Thickness Resting on Elastic Foundations
Journal of Materials and Engineering Structures, 2022 In this paper, the stability of rectangular cracked plates with nonlinearly variable thickness resting on the elastic foundations is studied. The thickness of the plate varies exponentially along the x-axis.
Vinh An LE, Minh Phuc PHAM, Tuan Anh BUI
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source