Results 71 to 80 of about 6,135,874 (298)
Curved and Layered Structures, 2019 In the present work, new inverse hyperbolic higher-order shear deformation theory (IHHSDT) is proposed and implemented for buckling analysis and free vibration analysis of porous Functionally Graded Material (FGM) plate on the foundation.
Kumar Rahul +3 more
doaj +1 more source
Dynamic response of infinite plate on orthotropic half-plane medium under moving loads
Yantu gongcheng xuebao, 2017 Based on the thin plate theory and the elastodynamics theory, the mechanical analysis model and the dynamic differential equations for the infinite elastic plate on orthotropic foundation under moving harmonic loads are established by taking the ...
ZHANG Chun-li 1, 2, WANG Bo 1, ZHU Yan-zhi 2
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Real Time Vehicle License Plate Recognition on Mobile Devices [PDF]
, 2013 Automatic license plate recognition is useful in many contexts such as parking control, law enforcement and vehicle background checking. The high cost and low portability of commercial systems makes them inaccessible to the majority of end users. However,
Alshahrani, Mohammed Ali A
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Vortex equilibria in flow past a plate [PDF]
, 2008 Families of vortex equilibria, with constant vorticity, in steady flow past a flat plate are computed numerically. An equilibrium configuration, which can be thought of as a desingularized point vortex, involves a single symmetric vortex patch located ...
McDonald, NR
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Cylindrical bending of orthotropic plate strip based on nth-order plate theory
Journal of Materials and Engineering Structures, 2014 In this paper, cylindrical bending of orthotropic plates is presented using nth-order plate theory. Classical plate theory and parabolic shear deformation theory of Reddy can be considered as special cases of present theory.
Atteshamuddin Shamshuddin Sayyad +2 more
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
PLATE-INJECTION INTO A SEPARATED SUPERSONIC BOUNDARY-LAYER [PDF]
, 1973 The structure of a supersonic laminar boundary layer near a flat plate is examined when fluid is injected into it with velocity of O(ε3U*[infty infinity]) over a distance of O(L). Here U*[infty infinity] is the undisturbed fluid velocity, L the length of
SMITH, FT, STEWARTS, K
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