Results 51 to 60 of about 117,425 (267)
Bending of the rigidly fixed elastic-plastic plate
Қарағанды университетінің хабаршысы. Математика сериясы, 2019 The number of plate structures include coatings, as well as box systems, working as a complete spatial system. The plate structures include systems elements of which are both rods and plates, for example, frame - panel structures with the bearing ...
L.S. Assetova +2 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Transactions of The Electrochemical Society, 1947 This paper describes a general study of the structural characteristics of chromium plate and of the mechanism of chromium plating. New fundamental data are presented on the crystal structure of chromium deposited from chromic acid solutions. In view of deposition conditions producing the various structural modifications, a hypothesis for the plating ...
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Dynamic response of infinite plate on orthotropic half-plane medium under moving loads
Yantu gongcheng xuebao, 2017 Based on the thin plate theory and the elastodynamics theory, the mechanical analysis model and the dynamic differential equations for the infinite elastic plate on orthotropic foundation under moving harmonic loads are established by taking the ...
ZHANG Chun-li 1, 2, WANG Bo 1, ZHU Yan-zhi 2
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
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Curved and Layered Structures, 2019 In the present work, new inverse hyperbolic higher-order shear deformation theory (IHHSDT) is proposed and implemented for buckling analysis and free vibration analysis of porous Functionally Graded Material (FGM) plate on the foundation.
Kumar Rahul +3 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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