Results 51 to 60 of about 871,347 (297)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Buckling of orthotropic plates with bimoments

open access: yesИнженерно-строительный журнал, 2015
The paper is dedicated to improvement of plate theory in order to take into account forces, moments and bimoments, generated by nonlinear law of displacement distribution in plate cross-sections.
M.K. Usarov
doaj   +1 more source

The concept of the habit plane and the phenomenological theories of the martensite transformation [PDF]

open access: yes, 1972
Three different interpretations of a martensite habit plane are in use: \ud \ud 1. (a) the plane of the plate of a plate-shaped crystal,\ud \ud 2. (b) a semi-coherent plane glissile interface,\ud \ud 3.
Klostermann, J.A.
core   +3 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Tensile instability and limit strain behavior of explosion-welded steel/Al plate considering interface defect characteristics

open access: yesJournal of Materials Research and Technology, 2023
Explosion-welded steel/Al composite plate has advantages of excellent conductivity, heat conductivity, light weight, and corrosion resistance. While the elongation of explosion-welded steel/Al composite plate can not been predicted by the traditional ...
Xiaomin Huang   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Transient Response Investigation of Cross-Ply Plates Using Refined Theory

open access: yesJournal of Engineering
Response of cross-ply plates subjected to transient load is obtained using five variables refined plate theory, and four variables plate theory. Equations of motion are derived through the principleof virtual work.
Ebtihal Abbas Sadiq   +1 more
doaj   +1 more source

A family of higher-order single layer plate models meeting $C^0_z$ -- requirements for arbitrary laminates [PDF]

open access: yes, 2019
In the framework of displacement-based equivalent single layer (ESL) plate theories for laminates, this paper presents a generic and automatic method to extend a basis higher-order shear deformation theory (polynomial, trigonometric, hyperbolic, ...) to ...
d'Ottavio, M.   +3 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Epithelial Folding Through Local Degradation of an Elastic Basement Membrane Plate

open access: yesAdvanced Physics Research
Epithelia are polarized layers of cells that line the outer and inner surfaces of organs. At the basal side, the epithelial cell layer is supported by a basement membrane, which is a thin polymeric layer of self‐assembled extracellular matrix (ECM) that ...
K. Yanín Guerra Santillán   +3 more
doaj   +1 more source

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