Results 31 to 40 of about 105,288 (139)

Food-specific serum IgG and symptom reduction with a personalized, unrestricted-calorie diet of six weeks in Irritable Bowel Syndrome (IBS)

Nutrition & Metabolism, 2020
Background Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life. Despite the prevalence of IBS, its etiology and pathophysiology are still to be fully understood, but immune ...
Mattia Cappelletti, Emiliana Tognon, Linda Vona, Katia Basello, Andrea Costanzi, Michela Carola Speciani, Attilio Francesco Speciani   +6 more
doaj   +1 more source

Compound Kushen Injection Induces Immediate Hypersensitivity Reaction Through Promoting the Production of Platelet-Activating Factor via de Novo Pathway

Frontiers in Pharmacology, 2021
Compound Kushen Injection (CKI) is a bis-herbal formulation extracted from Kushen (Radix Sophorae Flavescentis) and Baituling (Rhizoma Heterosmilacis Yunnanensis). Clinically, it is used as the adjuvant treatment of cancer.
Yuan Gao, Lina Hai, Lina Hai, Yuan Kang, Wenjie Qin, Fang Liu, Runlan Cai, Xiuwei Yang, Xiuwei Yang, Yun Qi   +9 more
doaj   +1 more source

Presence of platelet-activating factor-acetylhydrolase in milk

Journal of Lipid Research, 1993
Human milk contains numerous factors such as immunoglobulins, lactoferrin, lysozyme, macrophages, etc., which serve an immunoprotective role. Platelet-activating factor (PAF) is one of the most proinflammatory agents thus far described.
M Furukawa, H Narahara, K Yasuda, JM Johnston   +3 more
doaj   +1 more source

Effect of safflower yellow on platelet activating factor mediated platelet activation in patients with coronary heart disease

Bangladesh Journal of Pharmacology, 2012
The platelet aggregation and 5-HT release by washed platelet from coronary heart disease patients following platelet activating factor (PAF) treatment were detected by turbidimetry and O-phthalaldehyde assay.
Damin Huang, Yingmin Lu, Xiaohan Luo, Laixin Shi, Jinchun Zhang, Junxian Shen, Minmin Bao, Lei Song, Caiwen Wei, Hongsong Li, Zhihua Li   +10 more
doaj   +1 more source

Molecular and mechanistic characterization of platelet-activating factor-like bioactivity produced upon LDL oxidation

Journal of Lipid Research, 2005
Oxidation of LDL is thought to be involved in both initiating and sustaining atherogenesis through the formation of proinflammatory lipids and the covalent modification of LDL particles.
Nicolaos Androulakis, Hervé Durand, Ewa Ninio, Demokritos C. Tsoukatos   +3 more
doaj   +1 more source

Circulating biologically active oxidized phospholipids show on-going and increased oxidative stress in older male mice

Redox Biology, 2013
Background: The biologically active phospholipids Platelet-activating Factor (PAF) and oxidatively truncated phospholipids from chemical oxidation are increased in the circulation of rats subject to the oxidant stress of chronic ethanol ingestion ...
Jinbo Liu, Wei Li, Rui Chen, Thomas M. McIntyre   +3 more
doaj   +1 more source

Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers[S]

Journal of Lipid Research, 2010
The conversion of lysophosphatidic acid (LPA) to phosphatidic acid is carried out by the microsomal enzymes 1-acylglycerol-3-phosphate-O-acyltransferases (AGPATs).
Anil K. Agarwal, Abhimanyu Garg
doaj   +1 more source

Macrophage Derived Platelet Activating Factor Implicated in the Resolution Phase of Gouty Inflammation

International Journal of Inflammation, 2014
Human blood derived in vitro differentiated monocytes or macrophages are a population of cells which have been investigated over the years to determine the role these cells play in the resolution phase of gout.
Darshna Yagnik
doaj   +1 more source

Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β_1-42

Journal of Neuroinflammation, 2004
Background Neuronal loss in Alzheimer's or prion diseases is preceded by the accumulation of fibrillar aggregates of toxic proteins (amyloid-β1-42 or the prion protein).
Williams Alun, Salmona Mario, Bate Clive
doaj   +1 more source

Modulation by flavonoids of PAF and related phospholipids in endothelial cells during oxidative stress

Journal of Lipid Research, 2003
PAF-dependent transacetylase (TA) modifies the functions of platelet-activating factor (PAF), a potent inflammatory lipid, either by transferring the acetyl group from PAF to lysophospholipids (TAL activity), or to sphingosine (TAS activity) or by ...
Maria Luisa Balestrieri, Domenico Castaldo, Ciro Balestrieri, Lucio Quagliuolo, Alfonso Giovane, Luigi Servillo   +5 more
doaj   +1 more source