Results 61 to 70 of about 1,198,051 (418)

The release of platelet-activating factor from human endothelial cells in culture.

Journal of Immunology, 1983
The release of platelet-activating factor (PAF) from stimulated human endothelial cells (HEC) cultured from normal term, umbilical cord veins is described.
G. Camussi, M. Aglietta, F. Malavasi, C. Tetta, W. Piacibello, F. Sanavio, F. Bussolino   +6 more
semanticscholar   +1 more source

Glomerular platelet-activating factor levels and origin in experimental glomerulonephritis [PDF]

, 1990
Glomerular platelet-activating factor levels and origin in experimental glomerulonephritis. The content of platelet activating factor (PAF) in glomeruli isolated from rats with nephrotoxic serum glomerulonephritis (NSGN) was quantified at various stages ...
Lianos, Elias A., Zanglis, Anthony
core   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Physicochemical and functional identity of rabbit platelet-activating factor (PAF) released in vivo during IgE anaphylaxis with PAF released in vitro from IgE sensitized basophils.

Journal of Immunology, 1979
Platelet activating factor (PAF) released in vivo into the plasmas of rabbits during development of IgE-induced systemic anaphylactic shock had indistinguishable physicochemical and functional properties when compared with PAF released in vitro from ...
R. Neal Pinckard, Richard S. Farr, Donald J. Hanahan   +2 more
semanticscholar   +1 more source

Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor [PDF]

, 2013
Impaired healing is common in wounds infected with the major human pathogen Staphylococcus aureus, although the underlying mechanisms are poorly understood.
Amatruda, Ames, Amie K. Waller, Brown, Christopher Kumar, Clark, Corrigan, Deo, Draing, Dupré, Fedtke, Fischer, Fitzgerald, Haribabu, Hashimoto, Hwang, Iwasaki, Jonathan M. Gibbins, Kengatharan, Li, Lotz, Madsen, Mazer, Miajlovic, Moraes, Morath, Murphy, Nick, Peschel, Que, Reichmann, Rowley, Schmaler, Schröder, Schwarz, Shannon, Sheu, Siboo, Simon R. Clarke, Smyth, Stoll, Tanya Sage, Thomas Carr, Travers, van Langevelde, Vinogradov, Vogensen, Voorhees, Weidenmaier, Weidenmaier, Ye, Yeaman, Youssefian, Yue, Zhang, Zhang   +55 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Composite Quantile Factor Model [PDF]

arXiv, 2023
This paper introduces the method of composite quantile factor model for factor analysis in high-dimensional panel data. We propose to estimate the factors and factor loadings across multiple quantiles of the data, allowing the estimates to better adapt to features of the data at different quantiles while still modeling the mean of the data.
arxiv  

Platelet-Activating Factor-Receptor and Tumor Immunity [PDF]

, 2014
First described in 1972 by Benveniste and colleagues, platelet-activating factor (PAF) remains one of the potent phospholipid known to date. The role of PAF produced enzymatically in mediating diverse biological and pathophysiological processes including
Konger, Raymond L., Sahu, Ravi P., Travers, Jeffrey B.   +2 more
core  

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source