Results 11 to 20 of about 74,663 (286)

Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives. [PDF]

Molecules, 2019
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced histamine release from rabbit platelets producing antibodies in passive cutaneous anaphylaxis.
Lordan R, Tsoupras A, Zabetakis I, Demopoulos CA.   +3 more
europepmc   +2 more sources

Platelet-Activating Factor (PAF) in Allergic Rhinitis: Clinical and Therapeutic Implications. [PDF]

J Clin Med, 2019
Platelet-activating factor (PAF) is a lipid mediator involved in several allergic reactions. It is released from multiple cells of the immune system, such as eosinophils, neutrophils, and mast cells, and also exerts its effect on most of them upon ...
Muñoz-Cano RM, Casas-Saucedo R, Valero Santiago A, Bobolea I, Ribó P, Mullol J.   +5 more
europepmc   +2 more sources

Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR. [PDF]

J Exp Med, 2019
Platelet-activating factor (PAF) can drive pathophysiological inflammation, but the mechanism remains incompletely understood. Here, Deng et al. report that PAF activates the canonical NLRP3 inflammasome independently of its receptor PAFR.
Deng M, Guo H, Tam JW, Johnson BM, Brickey WJ, New JS, Lenox A, Shi H, Golenbock DT, Koller BH, McKinnon KP, Beutler B, Ting JP.   +12 more
europepmc   +2 more sources

Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children. [PDF]

Journal of Clinical Investigation, 1988
Masao Miwa, Teruki Miyake, Takashi Yamanaka, Junko Sugatani, Yasuo Suzuki, Susumu Sakata, Yoshio Araki, Masahiro Matsumoto   +7 more
openalex   +2 more sources

Inflammatory actions of platelet activating factor (Paf‐acether) in guinea‐pig skin [PDF]

British Journal of Pharmacology, 1983
John E. Morley, Clive Page, William Paul
openalex   +2 more sources

cDNA Cloning and Expression of Intracellular Platelet-activating Factor (PAF) Acetylhydrolase II [PDF]

Journal of Biological Chemistry, 1996
Platelet-activating factor (PAF) acetylhydrolase, which inactivates PAF by removing the acetyl group at the sn-2 position, is widely distributed in plasma and tissues.
Kenji Hattori, Hideki Adachi, Atsushi Matsuzawa, Kazuo Yamamoto, Masafumi Tsujimoto, Junken Aoki, Mitsuharu Hattori, Hiroyuki Arai, Keizo Inoue   +8 more
openalex   +2 more sources

Mouse and Human Eosinophils Degranulate in Response to Platelet-Activating Factor (PAF) and LysoPAF via a PAF-Receptor–Independent Mechanism: Evidence for a Novel Receptor [PDF]

Journal of Immunology, 2010
Kimberly D. Dyer, Caroline M. Percopo, Zhihui Xie, Zhao Yang, John Dongil Kim, Francis Davoine, Paige Lacy, Kirk M. Druey, Redwan Moqbel, Helene F. Rosenberg   +9 more
openalex   +2 more sources

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

The Platelet-Activating Factor Receptor’s Association with the Outcome of Ovarian Cancer Patients and Its Experimental Inhibition by Rupatadine

Cells, 2021
The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development.
Eileen Deuster, Ivi Hysenaj, Maja Kahaly, Elisa Schmoeckel, Doris Mayr, Susanne Beyer, Thomas Kolben, Anna Hester, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla   +14 more
doaj   +1 more source

Interaction of Platelet Activating Factor Acetyl Hydrolase (Paf Ah) Enzyme in Gln281 to Arg281 Mutation Toward Paf and Its Molecular Dynamic [PDF]

, 2014
Platelet Activating Factor Acetyl Hydrolase (PAF AH) or LpPLA2 is key enzyme in myocardial infarction catalyzes the sn-2 acetyl group of Platelet Activating Factor (PAF) into lyso PAF and acetate as non-potent inflammatory molecules.
Putri, J. F. (Jayarani), Rohman, M. S. (Muhammad), widodo, W. (widodo)   +2 more
core   +1 more source