Results 31 to 40 of about 24,574 (253)

No evidence for a putative involvement of platelet-activating factor in systemic lupus erythematosus without active nephritis

open access: yesMediators of Inflammation, 2003
Background: Platelet-activating factor (PAF) seems to be implicated in systemic lupus erythematosus (SLE) patients with associated renal diseases.Aims: In this study, we ensured the role of PAF in SLE patients without renal complications.
Yves Denizot   +7 more
doaj   +1 more source

A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]

open access: yes, 1993
Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR   +3 more
core   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

open access: yes, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT   +28 more
core   +1 more source

Platelet-activating factor (PAF) enhances guinea pig detrusor smooth muscle contractile activities by stimulating voltage-dependent Ca2+ channels and store-operated Ca2+ channels

open access: yesJournal of Pharmacological Sciences, 2023
We investigated the extracellular Ca2+ influx pathways involved in platelet-activating factor (PAF)-enhanced guinea pig detrusor smooth muscle (DSM) contractile activities.
Keisuke Obara   +5 more
doaj   +1 more source

Radiation therapy generates platelet-activating factor agonists [PDF]

open access: yes, 2016
Pro-oxidative stressors can suppress host immunity due to their ability to generate oxidized lipid agonists of the platelet-activating factor-receptor (PAF-R).
Chin-Sinex, Helen Jan   +13 more
core   +2 more sources

Effect of safflower yellow on platelet activating factor mediated platelet activation in patients with coronary heart disease

open access: yesBangladesh Journal of Pharmacology, 2012
The platelet aggregation and 5-HT release by washed platelet from coronary heart disease patients following platelet activating factor (PAF) treatment were detected by turbidimetry and O-phthalaldehyde assay.
Damin Huang   +10 more
doaj   +1 more source

Reversible cross-tolerance to platelet-activating factor signaling by bacterial toxins

open access: yesPlatelets, 2021
Bacterial toxins signaling through Toll-like receptors (TLRs) are implicated in the pathogenesis of many inflammatory diseases. Among the toxins, lipopolysaccharide (LPS) exerts its action via TLR-4 while lipoteichoic acid (LTA) and bacterial ...
Kandahalli Venkataranganayaka Abhilasha   +5 more
doaj   +1 more source

In Vitro Inhibitory Effect of SR 27417, a Potent Platelet-Activating Factor (PAF) Receptor Antagonist, on the PAF-Induced Bovine Platelet Aggregation [PDF]

open access: yes, 2000
The in vitro inhibitory effect of SR 27417, an antagonist of the platelet-activating factor (PAF) receptor, on PAF-induced platelet aggregation was studied in blood collected from seven healthy Friesien calves.
Bastos da Silva, Miriam   +4 more
core   +3 more sources

Platelet-activating factor acetylhydrolase and transacetylase activities in human aorta and mammary artery*

open access: yesJournal of Lipid Research, 2008
Platelet-activating factor (PAF), the potent phospholipid mediator of inflammation, is involved in atherosclerosis. Platelet-activating factor-acetylhydrolase (PAF-AH), the enzyme that inactivates PAF bioactivity, possesses both acetylhydrolase and ...
Demokritos C. Tsoukatos   +8 more
doaj   +1 more source

Apolipoprotein M [PDF]

open access: yes, 2004
Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL).
Lund University.   +4 more
core   +3 more sources

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