Results 31 to 40 of about 74,663 (286)

Differential fMet-Leu-Phe- and Platelet-activating Factor-induced Signaling Toward Ral Activation in Primary Human Neutrophils [PDF]

, 1999
We have measured the activation of the small GTPase Ral in human neutrophils after stimulation with fMet- Leu-Phe (fMLP), platelet activating factor (PAF), and granulocyte macrophage-colony stimulating factor and compared it with the activation of ...
Bos, J.L., Coffer, P.J., Koenderman, L., M'Rabet, Laura, Wolthuis, R.M.F., Zwartkruis, G.J.T.   +5 more
core   +5 more sources

Altered distribution of platelet-activating factor-acetylhydrolase activity between LDL and HDL as a function of the severity of hypercholesterolemia

Journal of Lipid Research, 2002
Platelet-activating factor-acetylhydrolase (PAF-AH) is a lipoprotein-associated phospholipase A2 capable of hydrolyzing platelet-activating factor (PAF) and oxidatively modified phospholipids.
Vasilis Tsimihodimos, Sonia-Athena P. Karabina, Afroditi P. Tambaki, Eleni Bairaktari, George Miltiadous, John A. Goudevenos, Marios A. Cariolou, M. John Chapman, Alexandros D. Tselepis, Moses Elisaf   +9 more
doaj   +1 more source

Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer

Mediators of Inflammation, 2004
This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients.
Yves Denizot, Véronique Truffinet, Stéphane Bouvier, Alain Gainant, Pierre Cubertafond, Muriel Mathonnet   +5 more
doaj   +1 more source

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]

, 1993
Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR, Nourshargh, S, Weg, VB, Williams, TJ   +3 more
core   +1 more source

Characterization of Canine Platelet Activation Induced by Platelet Activating Factor (PAF)

Journal of Veterinary Medical Science, 2008
Characteristics of the signal transduction in Platelet activating factor (PAF)-activated platelets and effects of anti-platelet agents on this response were investigated in vitro for potential therapeutic applications in canine endotoxemia. Blockade of the PAF receptor by a specific blocker has the strongest inhibitive effect on the PAF-induced ...
Ryo, Tsuchiya, Yumiko, Tatsuki, Satoshi, Kitao, Mitsuru, Furuichi, Sakurako, Neo, Masaharu, Hisasue, Takatsugu, Yamada, Kosaku, Kobayashi   +7 more
openaire   +3 more sources

No evidence for a putative involvement of platelet-activating factor in systemic lupus erythematosus without active nephritis

Mediators of Inflammation, 2003
Background: Platelet-activating factor (PAF) seems to be implicated in systemic lupus erythematosus (SLE) patients with associated renal diseases.Aims: In this study, we ensured the role of PAF in SLE patients without renal complications.
Yves Denizot, Eric Liozon, Laurence Guglielmi, Kim Ly, Pascale Soria, Véronique Loustaud, Elisabeth Vidal, Marie Odile Jauberteau   +7 more
doaj   +1 more source

Platelet-activating factor (PAF) enhances tumor necrosis factor production by alveolar macrophages. Prevention by PAF receptor antagonists and lipoxygenase inhibitors.

Journal of Immunology, 1989
The effect of platelet-activating factor (PAF) on TNF production by rat alveolar macrophages (AM) and the role of endogenous leukotriene B4 (LTB4) in this regulation were examined.
C. Dubois, É. Bissonnette, M. Rola-Pleszczynski   +2 more
semanticscholar   +1 more source

In Vitro Inhibitory Effect of SR 27417, a Potent Platelet-Activating Factor (PAF) Receptor Antagonist, on the PAF-Induced Bovine Platelet Aggregation [PDF]

, 2000
The in vitro inhibitory effect of SR 27417, an antagonist of the platelet-activating factor (PAF) receptor, on PAF-induced platelet aggregation was studied in blood collected from seven healthy Friesien calves.
Bastos da Silva, Miriam, Delaunois, Annie, Godeau, Jean-Marie, Gustin, Pascal, Lekeux, Pierre   +4 more
core   +3 more sources

Activation and desensitization of platelets by platelet-activating factor (PAF) derived from IgE-sensitized basophils. I. Characteristics of the secretory response

Journal of Experimental Medicine, 1976
The secretion of vasoactive amines from rabbit platelets induced by the platelet-activating factor (PAF) derived from IgE-sensitized rabbit basophils, was examined.
Henson Pm
semanticscholar   +1 more source