Results 51 to 60 of about 4,406,154 (211)
Journal of Lipid Research, 2001 Unmitigated oxidative stress is deleterious, as epitomized by CCl4 intoxication. In this well-characterized model of free radical-initiated damage, liver metabolism of CCl4 to CCl3.
Gopal K. Marathe +8 more
doaj +1 more source
Phytotherapy Research, EarlyView.This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren +10 more
wiley +1 more source
The Cardiovascular Effect of the Platelet Activator Factor
Journal of Biological Research, 2003 Platelet activating factor (PAF) is one of the most potent mediators found in mammals. PAF is a phospholipid with diverse and potent physiological effects; it is a mediator of cell – to cell communication,which may function either as a intercellular and
C. Penna
doaj +1 more source
Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases
Phytotherapy Research, EarlyView.Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin +7 more
wiley +1 more source
Molecules, 2010 Phylligenine, together with quebrachitol, stigmasterol and two aporphine alkaloids—oxoputerine and liriodenine—were isolated from the twigs of Mitrephora vulpina C.E.C. Fisch.
Khozirah Shaari +3 more
doaj +1 more source
Safety of Venom Immunotherapy in Pregnancy: A Multicentre Study
Allergy, EarlyView.Venom immunotherapy (VIT) during pregnancy, when maintenance dose is well tolerated, can be continued. No increased risk of adverse effects to VIT or safety concerns for the pregnancy or the newborns were observed. No decreased efficacy of VIT, in case of re‐stings, was reported.
Matteo Martini +20 more
wiley +1 more source
Platelet activating factor (PAF) as a mediator of injury in nephrotoxic nephritis [PDF]
, 1987 Platelet activating factor (PAF) as a mediator of injury in nephrotic nephritis. Release of acetyl glyceryl ether phosphorylcholine, platelet–activating factor (PAF), has been demonstrated to be associated with glomerular inflammatory damage in acute ...
Remuzzi, Giuseppe +13 more
core +1 more source
Platelet Activating Factor Synthesis and Metabolism in Intestinal Ischaemia-Reperfusion Injury
Mediators of Inflammation, 1994 The object of this study was to characterize the synthesis and metabolism of platelet activating factor (PAF) by intestinal mucosa subjected to ischaemia–reperfusion injury.
M. J. Mangino +3 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
Allergy, EarlyView.ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source