Results 141 to 150 of about 258,688 (303)

Ligand-independent activation of platelet-derived growth factor receptor β promotes vitreous-induced contraction of retinal pigment epithelial cells. [PDF]

BMC Ophthalmol, 2023
Duan Y, Wu W, Cui J, Matsubara JA, Kazlauskas A, Ma G, Li X, Lei H.   +7 more
europepmc   +1 more source

Lysyl oxidases directly control cell surface abundance of platelet-derived growth factor receptors and signaling in osteoblasts [PDF]

Wolfgang Jarolimek, Jessica Stolp, Lara Perryman, Nasi Huang, R. Hamilton, Alison D. Findlay, Amar Joshi, Jana Baskar, Katya Ravid   +8 more
openalex   +1 more source

Long‐term therapy‐free remission in a patient with platelet‐derived growth factor receptor beta‐rearranged myeloproliferative neoplasm [PDF]

, 2016
Marco Cerrano, Elena Crisà, Enrico Gottardi, Chiara Aguzzi, Mario Boccadoro, Dario Ferrero   +5 more
openalex   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

CP-673451, a Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces Apoptosis in Opisthorchis viverrini-Associated Cholangiocarcinoma via Nrf2 Suppression and Enhanced ROS. [PDF]

Pharmaceuticals (Basel), 2023
Duangdara J, Boonsri B, Sayinta A, Supradit K, Thintharua P, Kumkate S, Suriyonplengsaeng C, Larbcharoensub N, Mingphruedhi S, Rungsakulkij N, Muangkaew P, Tangtawee P, Vassanasiri W, Suragul W, Janvilisri T, Tohtong R, Bates DO, Wongprasert K.   +17 more
europepmc   +1 more source

Effects of Blocking Platelet-Derived Growth Factor-Receptor Signaling in a Mouse Model of Experimental Prostate Cancer Bone Metastases [PDF]

, 2003
Hisanori Uehara, Seung Jun Kim, Takashi Karashima, David L. Shepherd, D. Fan, R. Tsan, Jerald J. Killion, C. Logothetis, Paul Mathew, Isaiah J. Fidler   +9 more
openalex   +1 more source

A new approach to understanding T cell development: the isolation and characterization of immature CD4-, CD8-, CD3- T cell cDNAs by subtraction cloning [PDF]

, 1992
During T cell development in the mammalian thymus, immature T cells are observed that lack the cell surface markers CD4, CD8, and CD3. A subtracted cDNA library was constructed to isolate cDNAs that are specific for these immature T cells.
Gese, Elaine, Hood, Leroy, Orr, Sally L.
core  

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Site-selective Dephosphorylation of the Platelet-derived Growth Factor β-Receptor by the Receptor-like Protein-tyrosine Phosphatase DEP-1 [PDF]

, 2000
Marina Kovalenko, Karsten Denner, Jill Sandström, C. Persson, Steffen Groβ, Enrico Jandt, R. Vilella, Frank D. Böhmer, Arne Östman   +8 more
openalex   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source