Results 151 to 160 of about 258,688 (303)

Platelet-derived Growth Factor Receptor Alpha Gene Mutations in Vitiligo Vulgaris

, 2010
S.J. Xu, Yaoqi Zhou, Sen Yang, Yongcheng Ren, Chang Zhang, Cheng Quan, Min Gao, Chuan He, H Chen, J Hhan, Jie Chen, Yanhua Liang, Jiajia Yang, Liangdan Sun, Xiuxian Yin, Jianjun Liu, Xu Zhang   +16 more
openalex   +2 more sources

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Retracted: Association between the Platelet-Derived Growth Factor/Platelet-Derived Growth Factor Receptor System and Risk of Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Autoantibodies to the platelet-derived growth factor receptor in systemic sclerosis [PDF]

, 2006
Mariusz Puszczewicz, Grażyna Białkowska-Puszczewicz   +1 more
openalex  

Peptide-Based Targeting of the Platelet-Derived Growth Factor Receptor Beta [PDF]

, 2012
Vasileios Askoxylakis, Annabell Marr, Annette Altmann, Annette Markert, Walter Mier, Jürgen Debus, Peter E. Huber, Uwe Haberkorn   +7 more
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Angiotensin II stimulates phosphorylation of an ectodomain-truncated platelet-derived growth factor receptor-β and its binding to class IA PI3K in vascular smooth muscle cells [PDF]

, 2006
Benbo Gao, Hans Hansen, Hung‐Chi Chen, Edward P. Feener   +3 more
openalex   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

New natural compound inhibitors of PDGFRA (platelet-derived growth factor receptor α) based on computational study for high-grade glioma therapy. [PDF]

Front Neurosci, 2022
Yang W, Wang S, Zhang X, Sun H, Zhang M, Chen H, Cui J, Li J, Peng F, Zhu M, Yu B, Li Y, Yang L, Min W, Xue M, Pan L, Zhu H, Wu B, Gu Y.   +18 more
europepmc   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source