Results 181 to 190 of about 334,171 (270)

Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation. [PDF]

J Biol Chem, 2021
Wu K, Wu H, Lyu W, Kim Y, Furdui CM, Anderson KS, Koleske AJ.   +6 more
europepmc   +1 more source

Lovastatin inhibits platelet-derived growth factor (PDGF) stimulation of phosphatidylinositol 3-kinase activity as well as association of p85 subunit to tyrosine-phosphorylated PDGF receptor.

, 1993
Terence F. McGuire, Seth J. Corey, Saı̈d Sebti   +2 more
openalex   +1 more source

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo, Wen‐Ying Zheng, Qiong Zhang, Yan Yuan, Mei‐Qi Li, Kai Du, An‐Ran Gao, Li‐Jun Pei, Jie Xie, Wen‐Hao Chen, Long Zhang, Xiu‐Zhu Guo, Xiao‐Ran Yang, Chao Zeng, Guo‐Hua Yang, Min Deng   +15 more
wiley   +1 more source

Poor expression of miR‐195‐5p can assist the diagnosis of cerebral vasospasm after subarachnoid hemorrhage and predict adverse outcomes

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective Patients with spontaneous subarachnoid hemorrhage (SAH) may develop refractory arterial cerebral vasospasm (CVS), which is the leading cause of death in SAH patients. This study explored the clinical diagnostic value of serum miR‐195‐5p levels in CVS after SAH (SAH + CVS) and its relationship with the prognosis of SAH + CVS.
Yong Li, Senyuan Yang, Xiaobin Zhou, Runlong Lai   +3 more
wiley   +1 more source

Platelet-derived Growth Factor Receptor-α Induces Contraction Knots and Inflammatory Pain-like Behavior in a Rat Model of Myofascial Trigger Points. [PDF]

Anesthesiology
Liu Y, Jin F, Zhou L, Li X, Li X, Chen Q, Yang S, Sun J, Qi F.   +8 more
europepmc   +1 more source

Differential effects of carboxy-terminal sequence deletions on platelet-derived growth factor receptor signaling activities and interactions with cellular substrates.

, 1992
Klaus Seedorf, B Millauer, Günter Kostka, Joseph Schlessinger, A. Ullrich   +4 more
openalex   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy. [PDF]

Front Mol Biosci
Habib I, Sulaimani MN, Jairajpuri DS, Hussain A, Mohammad T, Alajmi MF, Shamsi A, Hassan MI.   +7 more
europepmc   +1 more source

A deletion in the extracellular domain of the alpha platelet-derived growth factor (PDGF) receptor differentially impairs PDGF-AA and PDGF-BB binding affinities.

, 1992
Mohammad A. Heidaran, Jungeun Yu, Roy A. Jensen, Jacalyn H. Pierce, S A Aaronson   +4 more
openalex   +1 more source

A Role for Src in Signal Relay by the Platelet-derived Growth Factor α Receptor [PDF]

, 1998
Julie A. Gelderloos, Stephan Rosenkranz, Chantal Bazenet, Andrius Kazlauskas   +3 more
openalex   +1 more source