Results 11 to 20 of about 126,363 (161)
Prenatal overexpression of platelet‐derived growth factor receptor A results in central nervous system hypomyelination [PDF]
Brain and Behavior, 2021 Background Platelet‐derived growth factor (PDGF) signaling, through the ligand PDGF‐A and its receptor PDGFRA, is important for the growth and maintenance of oligodendrocyte progenitor cells (OPCs) in the central nervous system (CNS). PDGFRA signaling is
Herminio Joey Cardona +4 more
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MicroRNA 219-5p inhibits alveolarization by reducing platelet derived growth factor receptor-alpha [PDF]
Respiratory Research, 2021 Background MicroRNA (miR) are small conserved RNA that regulate gene expression post-transcription. Previous genome-wide analysis studies in preterm infants indicate that pathways of miR 219-5p are important in infants with Bronchopulmonary Dysplasia ...
Amelia Freeman +10 more
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High tumor cell platelet‐derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma [PDF]
The Journal of Pathology: Clinical Research, 2021 Malignant pleural mesothelioma (MPM) has a rich stromal component containing mesenchymal fibroblasts. However, the properties and interplay of MPM tumor cells and their surrounding stromal fibroblasts are poorly characterized.
Hely Ollila +13 more
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Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP [PDF]
Scientific Reports, 2021 Following their inoculation by the bite of an infected Anopheles mosquito, the malaria parasite sporozoite forms travel from the bite site in the skin into the bloodstream, which transports them to the liver. The thrombospondin-related anonymous protein (
Ryan W. J. Steel +18 more
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Journal of Applied Hematology, 2015 Chronic eosinophilic leukemia (CEL) is a rare cause of eosinophilia. CEL is known to be associated with BCR-ABL fusion gene or rearrangement of platelet-derived growth factor receptor alpha (PDGFRA), (Platelet-derived growth factor receptor betaPDGFRB or
Khushboo Dewan, Col Tathagata Chatterjee
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Cancer Medicine, 2021 Olaratumab is a monoclonal antibody that specifically binds to platelet‐derived growth factor receptor alpha (PDGFRα) and blocks receptor activation. We conducted a phase 1 trial to evaluate the safety of olaratumab and determine a recommended dose in ...
Leo Mascarenhas +14 more
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Stem Cell Research, 2023 PDGFRB encodes platelet-derived growth factor receptor beta (PDGFR-β), a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family.
Seongyea Jo +5 more
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Anatolian Journal of Cardiology, 2020 Objective: Microvascular angina (MVA) is a coronary microcirculation disease. Research on microcirculatory dysfunction has revealed several biomarkers involved in the etiopathogenesis of MVA.
Gamze Aslan +5 more
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Freeze-Dried Platelet-Rich Plasma Induces Osteoblast Proliferation via Platelet-Derived Growth Factor Receptor-Mediated Signal Transduction [PDF]
Asian Spine Journal, 2020 Study Design Controlled laboratory study. Purpose This study aimed to evaluate the in vitro pharmacological activity of growth factors (GFs) in freeze-dried platelet-rich plasma (FD-PRP) after storage for 4 weeks.
Hideyuki Kinoshita +16 more
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Frontiers in Oncology, 2018 Chondrosarcoma is a rare malignancy characterized by the production of cartilage matrix, displaying heterogeneous histopathology and clinical behavior.
Onoufrios Tsavaris +7 more
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