Results 41 to 50 of about 500,127 (414)

Chronic eosinophilic leukemia with Fip 1-like 1-platelet-derived growth factor receptor alpha mutation: A rare case report

open access: yesJournal of Applied Hematology, 2015
Chronic eosinophilic leukemia (CEL) is a rare cause of eosinophilia. CEL is known to be associated with BCR-ABL fusion gene or rearrangement of platelet-derived growth factor receptor alpha (PDGFRA), (Platelet-derived growth factor receptor betaPDGFRB or
Khushboo Dewan, Col Tathagata Chatterjee
doaj   +1 more source

Platelet-derived growth factors and their receptors: Structural and functional perspectives [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
The four types of platelet-derived growth factors (PDGFs) and the two types of PDGF receptors (PDGFRs, which belong to class III receptor tyrosine kinases) have important functions in the development of connective tissue cells. Recent structural studies have revealed novel mechanisms of PDGFs in propeptide loading and receptor recognition/activation ...
Xiaolin He, Xiaoyan Chen, Po Han Chen
openaire   +3 more sources

Freeze-Dried Platelet-Rich Plasma Induces Osteoblast Proliferation via Platelet-Derived Growth Factor Receptor-Mediated Signal Transduction [PDF]

open access: yesAsian Spine Journal, 2020
Study Design Controlled laboratory study. Purpose This study aimed to evaluate the in vitro pharmacological activity of growth factors (GFs) in freeze-dried platelet-rich plasma (FD-PRP) after storage for 4 weeks.
Hideyuki Kinoshita   +16 more
doaj   +1 more source

PDGFRB (platelet-derived growth factor receptor, beta polypeptide) [PDF]

open access: yes, 2005
Review on PDGFRB (platelet-derived growth factor receptor, beta polypeptide), with data on DNA, on the protein encoded, and where the gene is ...
Vizmanos, JL
core   +1 more source

PDGFRA (platelet-derived growth factor receptor, alpha polypeptide) [PDF]

open access: yes, 2015
Review on PDGFRA (platelet-derived growth factor receptor, alpha polypeptide), with data on DNA, on the protein encoded, and where the gene is ...
Al, Bahar S, Zamecnikova, A
core   +1 more source

Epitope Specificity Determines Pathogenicity and Detectability of Anti–Platelet‐Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis

open access: yesArthritis & Rheumatology, 2015
To identify the epitopes recognized by autoantibodies targeting platelet‐derived growth factor receptor α (PDGFRα) in systemic sclerosis (SSc) and develop novel assays for detection of serum anti‐PDGFRα autoantibodies.
G. Moroncini   +13 more
semanticscholar   +1 more source

Generation of a PDGFRB-mCherry knock-in reporter human induced pluripotent stem cell line (KITi001-A-1), using CRISPR/Cas9 nuclease

open access: yesStem Cell Research, 2023
PDGFRB encodes platelet-derived growth factor receptor beta (PDGFR-β), a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family.
Seongyea Jo   +5 more
doaj  

Evaluation of serum platelet-derived growth factor receptor-ß and brain-derived neurotrophic factor levels in microvascular angina

open access: yesAnatolian Journal of Cardiology, 2020
Objective: Microvascular angina (MVA) is a coronary microcirculation disease. Research on microcirculatory dysfunction has revealed several biomarkers involved in the etiopathogenesis of MVA.
Gamze Aslan   +5 more
doaj   +1 more source

Potential mechanisms involved on how systemic IgG antibodies specific to vascular endothelial growth factor (VEGF) and induced by active immunotherapy decrease platelet derived free-VEGF

open access: yesPlatelets, 2022
CIGB-247 is a vascular endothelial growth factor (VEGF)-based active immunotherapy and it is currently under investigation for cancer treatment. This specific active immunotherapy encompasses two vaccine candidates that use a human VEGF variant molecule ...
Javier Sánchez Ramírez   +3 more
doaj   +1 more source

The platelet-derived growth factor receptor alpha promoter-directed expression of cre recombinase in mouse placenta. [PDF]

open access: yes, 2019
BackgroundNumerous pathologies of pregnancy originate from placental dysfunction. It is essential to understand the functions of key genes in the placenta in order to discern the etiology of placental pathologies.
Lee, Samuel   +4 more
core   +1 more source

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