Results 111 to 120 of about 189,293 (252)

Associations of serum 25-hydroxyvitamin D with hsCRP and other novel inflammatory biomarkers in children: a cross-sectional study

BMJ Open
Objective Previous studies have shown the anti-inflammatory effect of 25-hydroxyvitamin D (25(OH)D) and the crucial roles of high-sensitive C reactive protein (hsCRP) and novel inflammatory markers (red blood cell distribution width–platelet count ratio (
Liang Gao, Xiaojing Xu, Hongli Dong, Feiying Wang, Yufei Ni   +4 more
doaj   +1 more source

Prognostic value of blood count parameters in patients with acute coronary syndrome

Indian Heart Journal, 2018
Background: Recent studies have shown that complete blood count (CBC) parameters can effectively predict long-term mortality and re-infarction rates in acute coronary syndrome (ACS).
Arsalan Majeed Adam, Ather Hasan Rizvi, Amna Haq, Rabia Naseem, Aiman Rehan, Ali Tariq Shaikh, Abdul Haseeb Abbas, Ansab Godil, Arif Ali, Muhammad Saad Ali Mallick, Muhammad Shahzeb Khan, Muhammad Nawaz Lashari   +11 more
doaj   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Cervenak, László, Förhécz, Zsolt, Gombos, Tímea, Hársfalvi, Jolán, Jánoskuti, Lívia, Kunde, Jan, Makó, Veronika, Papassotiriou, Jana, Pozsonyi, Zoltán, Prohászka, Zoltán   +10 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

A The ratio of neutrophils l and the mean platelet volume to platelet count ratio as risk factors for febrile convulsions in Zakho

Zanco Journal of Medical Sciences
Background and objective: The most prevalent cause of convulsions in young children is febrile convulsions. The ratio of neutrophils to lymphocytes (NLR), the mean platelet volume (MPV), and the platelet count are indicators of inflammation.
Sherzad A. Mosa, Akrem M. Atrushi, Farhad Shaker Armishty, Mehvan Sh. Abdulrahman   +3 more
doaj   +1 more source

BMQ [PDF]

, 1963
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan, Bagnoli, Thomas, Barber, Doris E., Cocchiarella, John P., Duke, Martin, Estes, J. Worth, Friedlander, Walter J., Goldsmith, Harry S., Gooding, Gretchen W., Goofman, Max L., Haseotes, Hytho V., Hass, Gerald, Hastings, A. Baird, Jackson, David R., Johnson, David S., Kechejian, Sarkis J., Kramer, Philip, Litman, George I., Madoff, Irving M., McLellan, Patricia A., O'Hara, Vincent S., Peabody, C. Newton, Pryles, Charles V., Small, Donald M., Tedeschi, Luke G., Walker, Sydney, III   +25 more
core  

Aging-Related Decline of Glutathione Peroxidase 3 and Risk of Cardiovascular Events in Patients With Atrial Fibrillation [PDF]

, 2016
BACKGROUND: Experimental studies demonstrated that glutathione peroxidase 3 (GPx3), an antioxidant enzyme that catabolizes hydrogen peroxide, protects against thrombosis. Little is known about its role in cardiovascular disease. METHODS AND RESULTS:
Carnevale, Roberto, Farcomeni, Alessio, Menichelli, Danilo, Nocella, Cristina, Pastori, Daniele, Pignatelli, Pasquale, Violi, Francesco   +6 more
core   +1 more source

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

Advanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang, Feng‐Ming Li, Yi‐Fan Tu, Ke‐Ke Feng, Cheng‐Lei Li, Shi‐Cheng Tian, Yong‐Shan Hu, Jing‐Wei Shao, Zhen‐Hua Liu   +8 more
wiley   +1 more source

Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem. [PDF]

, 2019
Rap1 GTPases bind effectors, such as RIAM, to enable talin1 to induce integrin activation. In addition, Rap1 binds directly to the talin1 F0 domain (F0); however, this interaction makes a limited contribution to integrin activation in CHO cells or ...
Alexandre R. Gingras, Andrew J. Valadez, Anthis, Bromberger, Calderwood, Camp, Critchley, Frederic Lagarrigue, Frojmovic, Gingras, Goult, Haling, Han, Hynes, Klapproth, Klaus Ley, Lagarrigue, Lagarrigue, Lee, Marcus Zorovich, Mark H. Ginsberg, Miguel Alejandro Lopez-Ramirez, Monica N. Cuevas, Nicolas Seban, Nieswandt, O’Toole, Petrich, Petrich, Plak, Shattil, Shattil, Simonson, Song, Stefanini, Stritt, Su, Sun, Tadokoro, Vranken, Wegener, William B. Kiosses, Wilma McLaughlin, Ye, Zeiler, Zhu   +44 more
core   +2 more sources

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source