Results 91 to 100 of about 1,682,982 (408)

Platelet-Derived PCSK9 Is Associated with LDL Metabolism and Modulates Atherothrombotic Mechanisms in Coronary Artery Disease [PDF]

open access: gold, 2021
Álvaro Petersen-Uribe   +11 more
openalex   +1 more source

Platelet Signaling and Disease: Targeted Therapy for Thrombosis and Other Related Diseases

open access: yesPharmacological Reviews, 2018
Platelets are essential for clotting in the blood and maintenance of normal hemostasis. Under pathologic conditions such as atherosclerosis, vascular injury often results in hyperactive platelet activation, resulting in occlusive thrombus formation ...
J. Yeung, Wenjie Li, M. Holinstat
semanticscholar   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani   +38 more
wiley   +1 more source

Casein kinase I isoforms contribute to platelet activation and thrombogenesis via RIPK3–MLKL signaling

open access: yesCommunications Biology
Platelets are small, enucleate blood cells having life span of 10-12 days that play fundamental role in hemostasis and thrombosis. Casein Kinase 1 (CK1) is a serine/threonine-specific protein kinase that governs multiple cellular processes including ...
Vipin Singh   +3 more
doaj   +1 more source

Biomimetic implant surface functionalization with liquid L-PRF products: in vitro study [PDF]

open access: yes, 2018
Objective: Platelet-rich fibrin (PRF) clots and membranes are autologous blood concentrates widely used in oral surgical procedures; less is known, however, about the liquid formulations of such products.
BOZZUTO, GIUSEPPINA   +5 more
core   +2 more sources

Platelet Size in Relation to Platelet Age

open access: yesExperimental Biology and Medicine, 1964
SummaryThe frequency distribution of platelet sizes in platelet populations of various ages was investigated using a Coulter Electronic Particle Counter, model B, and a particle size distribution plotter. Platelets were obtained from male Sprague-Dawley rats, young platelets from rats recovering from thrombocytopenia induced with platelet-specific ...
T P, MCDONALD, T T, ODELL, D G, GOSSLEE
openaire   +2 more sources

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen   +11 more
wiley   +1 more source

Prion protein fragment (106–126) activates NLRP3 inflammasome and promotes platelet-monocyte/neutrophil interactions, potentially contributing to an inflammatory state

open access: yesFrontiers in Cell and Developmental Biology
IntroductionPrion diseases are neurodegenerative disorders where infectious prion proteins (PrP) featuring an amyloidogenic amino acid sequence, PrP (106–126), accumulate in the brain leading to neuroinflammation while it can also access circulation by ...
Rashmi Verma   +4 more
doaj   +1 more source

Impact of walkability with regard to physical activity in the prevention of diabetes

open access: yesGeospatial Health, 2017
Walkability, a component of urban design intended to facilitate pedestrian traffic, depends on parameters associated with the connectivity of routes, population density and availability of destinations in the neighbourhood.
Carlos Mena   +4 more
doaj   +1 more source

Platelet signaling--blood's great balancing act [PDF]

open access: yes, 2015
The antagonistic balance between CalDAG-GEFI and RASA3 signaling is critical for the fine-tuning of platelet adhesiveness, both in the circulation and at sites of vascular ...
Bergmeier, Wolfgang, Stefanini, Lucia
core   +2 more sources

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