Results 121 to 130 of about 817,954 (300)
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance
, 2008 BACKGROUND: Thrombotic events still occur in aspirin-treated patients with coronary artery disease. METHODS AND RESULTS: To better understand aspirin "resistance," serum thromboxane B2 (TXB2) and flow cytometric measures of arachidonic acid-induced ...Frelinger, Andrew L. III, Barnard, Marc R., Furman, Mark I., Li, Youfu, Fox, Marsha L., Linden, Matthew D., Michelson, Alan D. +6 morecore +1 more sourceTreatment of critical bleeding events in patients with immune thrombocytopenia: a protocol for a systematic review and meta-analysis
Systematic ReviewsBackground Critical bleeding events in adults and children with ITP are medical emergencies; however, evidence-based treatment protocols are lacking. Due to the severe thrombocytopenia, (typically platelet count less than 20 × 109/L), a critical bleed ...Emily Sirotich, Hasmik Nazaryan, Saifur Rahman Chowdhury, Gordon Guyatt, Arnav Agarwal, Russell Leong, Aaron Wen, Emily Xu, Bonnie Liu, Sushmitha Pallapothu, Preksha Rathod, Henry Y. Kwon, Jared Dookie, Amirmohammad Shafiee, Jay Charness, Jennifer DiRaimo, Dale Paynter, Barbara Pruitt, Gail Strachan, Rachel Couban, Zhikang Ye, Donald M. Arnold +21 moredoaj +1 more sourceDirect oral anticoagulants in cirrhosis: Rationale and current evidenceKeypoints
JHEP ReportsSummary: Cirrhosis is a major health concern worldwide with a complex pathophysiology affecting various biological systems, including all aspects of haemostasis.Cindy Pereira Portela, Lucas A. Gautier, Maxime G. Zermatten, Montserrat Fraga, Darius Moradpour, Debora Bertaggia Calderara, Alessandro Aliotta, Lucas Veuthey, Andrea De Gottardi, Guido Stirnimann, Lorenzo Alberio +10 moredoaj +1 more sourceStructural Power Composites Based on High Mass Loading Zn‐Ion Hybrid Supercapacitors with Metal Mesh Current Collectors and Aramid Nanofiber/Glass Fiber Composite Electrolytes
Advanced Functional Materials, EarlyView.A multifunctional structural power composite is developed by integrating high‐mass‐loading Zn‐ion hybrid supercapacitors with metal mesh current collectors and aramid nanofiber‐based composite electrolytes, enabling simultaneous load‐bearing capability and enhanced areal energy storage.Yuseung Choi, Gilyong Shin, Hoyeon Lee, Eun Jae Nam, Byeong Jun So, Sungryul Yun, Fu‐Kuo Chang, Jei Gyeong Jeon, Tae June Kang +8 morewiley +1 more sourceTailoring Light Management in All‐Perovskite Tandem Solar Cells: The Impact of Nanotextures
Advanced Functional Materials, EarlyView.To further improve the power conversion efficiency of all‐perovskite tandem solar cells, light management strategies need to be implemented. Front‐sided nanotextures reduce reflection losses, which boosts light absorption, thus increasing the tandem JSC, which is further supported by reducing parasitic absorption.Sebastian Berwig, Yeonghun Yun, Doyun Im, Isabella Taupitz, Alexandros Cruz, Marlene Härtel, Bor Li, Kevin J. Prince, Hanifah Winarto, Thomas W. Gries, Klaus Jäger, Florian Riesebeck, Daniele Mantione, Sharon Monaci, Silvia Mariotti, Vishnu Vijayakumar, René A. J. Janssen, Sangwook Lee, Bernd Stannowski, Christiane Becker, Philipp Tockhorn, Steve Albrecht +21 morewiley +1 more sourceNew highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors
, 2016 Currently approved platelet adenosine diphosphate (ADP) receptor antagonists target only the platelet P2Y12 receptor. Moreover, especially in patients with acute coronary syndromes, there is a strong need for rapidly acting and reversible antiplatelet ...Yanachkov, Ivan B., Yanachkova, Milka, Gremmel, Thomas, Chang, Hung, Dix, Edward J., Frelinger, Andrew L III, Wright, George E., Berny-Lang, Michelle A., Michelson, Alan D. +8 morecore +1 more sourceIn response to the comment by Hechler et al.: Amotosalen/UVA pathogen inactivation technology reduces platelet activatability, induces apoptosis and accelerates clearance.
Haematologica, 2017 Simona Stivala, Sara Gobbato, Laura Infanti, Martin F. Reiner, Nicole Bonetti, Sara C. Meyer, Giovanni G. Camici, Thomas F. Lüscher, Andreas Buser, Juerg H. Beer +9 moredoaj +1 more sourceMultifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy
Advanced Functional Materials, EarlyView.Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang +16 morewiley +1 more sourcePressure‐Assisted Dimensional Transformation of 2D Hydrogenated Borophene into 0D Boron Quantum Dots
Advanced Functional Materials, EarlyView.Hydrogenated borophene (HB) is transformed into distinct boron nanostructures through a solvent‐free thermal process. Under flowing nitrogen, hydrogen escape promotes reconstruction into B2O3 nanoplatelets, whereas hydrogen‐induced pressure under sealed conditions facilitates fragmentation into boron quantum dots.Ozden Gunes Yildiz, Ramin Yazdaanpanah, Yongfeng Guo, Pouriya Naziri, Sachin Kulkarni, Martina Mercurio, Maria Cristina Larciprete, Ilaria Fratoddi, Paul Simon, Wan‐Lu Li, Koray Aydin, Umut Aydemir +11 morewiley +1 more source