Results 151 to 160 of about 1,259,805 (359)

Ribosomes in platelets protect the messenger [PDF]

, 2017
Jesse W. Rowley, Andrew S. Weyrich
openalex   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Dysregulation of platelet serotonin, 14–3–3, and GPIX in sudden infant death syndrome

Scientific Reports
Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality, but the underlying cause(s) are unclear. A subset of SIDS infants has abnormalities in the neurotransmitter, serotonin (5-hydroxytryptamine [5-HT]) and the ...
Andrew L. Frelinger, Robin L. Haynes, Richard D. Goldstein, Michelle A. Berny-Lang, Anja J. Gerrits, Molly Riehs, Elisabeth A. Haas, Brankica Paunovic, Othon J. Mena, Steven C. Campman, Ginger L. Milne, Lynn A. Sleeper, Hannah C. Kinney, Alan D. Michelson   +13 more
doaj   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics

Scientific Reports
Distinct platelet activation patterns are elicited by the tyrosine kinase-linked collagen receptor glycoprotein VI (GPVI) and the G-protein coupled protease-activated receptors (PAR1/4) for thrombin.
Delia I. Fernández, Sara Troitiño, Vladimír Sobota, Bibian M. E. Tullemans, Jinmi Zou, Helma van den Hurk, Ángel García, Saman Honarnejad, Marijke J. E. Kuijpers, Johan W. M. Heemskerk   +9 more
doaj   +1 more source

Intracellular Ca2+ rise in human platelets induced by polymorphonuclear-leucocyte-derived cathepsin G [PDF]

, 1992
Marina Molino, M Di Lallo, Giovanni de Gaetano, Chiara Cerletti   +3 more
openalex   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

The proteome of circulating extracellular vesicles and their functional effect on platelets vary with the isolation method

Scientific Reports
Extracellular vesicles (EVs) play a crucial role in cell-to-cell communication and serve as a source of biomarkers in several pathologies. In this study, we aimed to characterize plasma-derived EVs isolated by ultracentrifugation (UC) or size exclusion ...
Eva M. Fernández-Sáez, Susana B. Bravo, Carmen Pena, Ángel García   +3 more
doaj   +1 more source

Primum non confundere: whole blood versus apheresis platelet debate continues [PDF]

, 2016
Zbigniew M. Szczepiorkowski, Jeffrey McCullough, Darrell J. Triulzi   +2 more
openalex   +1 more source

Platelet and leukocyte count assay for thrombogenicity screening of biomaterials and medical devices: Evaluation and improvement of ASTM F2888 test standard

, 2021
Qijin Lu, Joshua M. Nehrer, Jiaming Li, Megan A. Jamiolkowski, Jean E. Rinaldi, Richard A. Malinauskas   +5 more
openalex   +2 more sources