Results 1 to 10 of about 1,044,846 (392)

Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β_1-42

Journal of Neuroinflammation, 2004
Background Neuronal loss in Alzheimer's or prion diseases is preceded by the accumulation of fibrillar aggregates of toxic proteins (amyloid-β1-42 or the prion protein).
Williams Alun, Salmona Mario, Bate Clive
doaj   +1 more source

Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells [PDF]

, 1992
Specific antibodies against rap1A and rap1B small GTP-binding proteins were generated by immunization of rabbits with peptides derived from the C-terminus of the processed proteins.
Frank, R., Gausepohl, H., Klinz, F. J., Schultz, Günter, Schwaner, I., Seifert, Roland   +5 more
core   +1 more source

Production of platelet-activating factor in slugs.

Journal of Lipid Research, 1991
The land slug, Incilaria bilineata, was shown to contain a large amount of 1-O-alkyl-2-acyl (long chain)-sn-glycero-3-phosphocholine, which accounts for as much as 47% of the choline glycerophospholipid fraction. Since this unique either phospholipid has
T Sugiura, T Ojima, T Fukuda, K Satouchi, K Saito, K Waku   +5 more
doaj  

Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor [PDF]

, 2013
Impaired healing is common in wounds infected with the major human pathogen Staphylococcus aureus, although the underlying mechanisms are poorly understood.
Amatruda, Ames, Amie K. Waller, Brown, Christopher Kumar, Clark, Corrigan, Deo, Draing, Dupré, Fedtke, Fischer, Fitzgerald, Haribabu, Hashimoto, Hwang, Iwasaki, Jonathan M. Gibbins, Kengatharan, Li, Lotz, Madsen, Mazer, Miajlovic, Moraes, Morath, Murphy, Nick, Peschel, Que, Reichmann, Rowley, Schmaler, Schröder, Schwarz, Shannon, Sheu, Siboo, Simon R. Clarke, Smyth, Stoll, Tanya Sage, Thomas Carr, Travers, van Langevelde, Vinogradov, Vogensen, Voorhees, Weidenmaier, Weidenmaier, Ye, Yeaman, Youssefian, Yue, Zhang, Zhang   +55 more
core   +1 more source

Platelet activating factor (PAF) induced release of platelet factor 4 (PF4) in vitro and during IgE anaphylaxis in the rabbit.

Journal of Immunology, 1979
Basophil-derived platelet activating factor (PAF) was shown to induce the release of platelet factor 4 (PF4), a specific platelet protein, from isolated, washed rabbit platelets.
L. McManus, C. Morley, S. P. Levine, R. N. Pinckard   +3 more
semanticscholar   +1 more source

Circulating biologically active oxidized phospholipids show on-going and increased oxidative stress in older male mice

Redox Biology, 2013
Background: The biologically active phospholipids Platelet-activating Factor (PAF) and oxidatively truncated phospholipids from chemical oxidation are increased in the circulation of rats subject to the oxidant stress of chronic ethanol ingestion ...
Jinbo Liu, Wei Li, Rui Chen, Thomas M. McIntyre   +3 more
doaj   +1 more source

Medical treatment of ascites in cirrhosis [PDF]

, 1993
Medical treatment of cirrhotic ascites is essentially supportive, dictated by the patient's discomfort, impaired cardiovascular or respiratory function and potential for infection. Treatment of ‘simple’ ascites (moderate fluid accumulation, serum albumin
Alexander L. Gerbes, Bernardi, Bichet, Bosch, Broekhuysen, Caramelo, Conn, DiBona, Epstein, Faloon, Fogel, Fuller, Ganger, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Ginès, Gregory, Guarner, Henriksen, Hoermann, Jüngst, Karnad, Keppler, Laffi, Lenz, Levy, Moore, Perez-Ayuso, Petrillo, Pockros, Ring-Larsen, Schrier, Schölmerich, Shear, Sherlock   +41 more
core   +1 more source

Platelet aggregometry assay for evaluating the effects of platelet agonists and antiplatelet compounds on platelet function in vitro

MethodsX, 2019
Platelet aggregometry assays are generally used for the analysis of platelet function but can also be adapted for further research and therapy focused applications.
Alexandros Tsoupras, Ioannis Zabetakis, Ronan Lordan   +2 more
doaj  

Interaction of Platelet Activating Factor Acetyl Hydrolase (Paf Ah) Enzyme in Gln281 to Arg281 Mutation Toward Paf and Its Molecular Dynamic [PDF]

, 2014
Platelet Activating Factor Acetyl Hydrolase (PAF AH) or LpPLA2 is key enzyme in myocardial infarction catalyzes the sn-2 acetyl group of Platelet Activating Factor (PAF) into lyso PAF and acetate as non-potent inflammatory molecules.
Putri, J. F. (Jayarani), Rohman, M. S. (Muhammad), widodo, W. (widodo)   +2 more
core   +1 more source

Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-containing lipoproteins

Journal of Lipid Research, 2003
Human plasma platelet-activating factor acetylhydrolase (PAF-AH) is an enzyme associated mainly with the apolipoprotein B (apoB)-containing lipoproteins and primarily with LDL. A small proportion of enzymatic activity is also associated with HDL.
Vasilis Tsimihodimos, Anna Kakafika, Afroditi P. Tambaki, Eleni Bairaktari, M.John Chapman, Moses Elisaf, Alexandros D. Tselepis   +6 more
doaj