Results 1 to 10 of about 1,047,417 (393)
Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
Journal of Occupational Medicine and Toxicology, 2008 Background Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
Groneberg David A +3 more
doaj +5 more sources
To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase
Journal of Lipid Research, 2014 Mounting ambiguity persists around the functional role of the plasma form of platelet-activating factor acetylhydrolase (PAF-AH). Because PAF-AH hydrolyzes PAF and related oxidized phospholipids, it is widely accepted as an anti-inflammatory enzyme.
Gopal Kedihitlu Marathe +5 more
doaj +2 more sources
Impact of targeting the platelet-activating factor and its receptor in cancer treatment [PDF]
Military Medical ResearchThe lipid mediator platelet-activating factor (PAF) and its receptor (PAFR) signaling play critical roles in a wide range of physiological and pathophysiological conditions, including cancer growth and metastasis.
Kimya Qaderi +3 more
doaj +2 more sources
Platelet activating factor in allergies
International Journal of Immunopathology and Pharmacology, 2015 The platelet-activating factor (PAF) produced and released by mast cells, basophils, neutrophils, eosinophils, fibroblasts, platelets, endothelial cells, and even cardiac muscle cells plays an important role in inflammatory and thrombotic diseases. PAF has been shown to be an important mediator in anaphylaxis. Serum level of the factor correlates with
K. Pałgan, Z. Bartuzi
semanticscholar +4 more sources
Japanese Journal of Thrombosis and Hemostasis, 1991 血 小 板 活 性 化 因 子(platelet-activating factor, PAF)は,現 在 の と こ ろ唯 一 非 常 に 強 力 な 生 理 活 性 を持 つ リン脂 質 で あ り,そ の 本 体 は ア ル キ ル エ ー テ ル 型 コ リ ン リ ン脂 質(1-0-alkyl2-acetyl-sn-glycero-3-phosphocholine, alkylacetyl-GPCho)で あ る(Fig.1).そ の 特 異 的 な構 造 の 一 つ で あ る ア ル キ ...
T. Kawasaki, Jun-ichi Kambayashi
semanticscholar +4 more sources
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer [PDF]
Cancer Cell International, 2021 Background Ovarian cancer is the leading cause of death from gynaecologic illnessed worldwide. Platelet-activating factor acetyl hydrolase IB2 (PAF-AH IB2) is an intracellular serine esterase that hydrolyzes platelet-activating factor, a G-protein-like ...
YingYing He +3 more
doaj +2 more sources
Macrophage Derived Platelet Activating Factor Implicated in the Resolution Phase of Gouty Inflammation [PDF]
International Journal of Inflammation, 2014 Human blood derived in vitro differentiated monocytes or macrophages are a population of cells which have been investigated over the years to determine the role these cells play in the resolution phase of gout.
Darshna Yagnik
doaj +3 more sources
Hearts, 2021 The purpose of this literature review is to gain an overview of the role of platelet-activating factor (PAF) within each of the body systems and how it contributes to normal and pathophysiological states.
Nilank Shah, Karan Kumar, Nikeith Shah
doaj +1 more source
Cells, 2021 The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development.
Eileen Deuster +14 more
doaj +1 more source
UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment
Frontiers in Immunology, 2022 Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the major cause of skin carcinogenesis.
Timothy C. Frommeyer +10 more
doaj +1 more source