Results 1 to 10 of about 200,980 (357)

Macrophage Derived Platelet Activating Factor Implicated in the Resolution Phase of Gouty Inflammation [PDF]

International Journal of Inflammation, 2014
Human blood derived in vitro differentiated monocytes or macrophages are a population of cells which have been investigated over the years to determine the role these cells play in the resolution phase of gout.
Darshna Yagnik
doaj   +3 more sources

Impact of targeting the platelet-activating factor and its receptor in cancer treatment [PDF]

Military Medical Research
The lipid mediator platelet-activating factor (PAF) and its receptor (PAFR) signaling play critical roles in a wide range of physiological and pathophysiological conditions, including cancer growth and metastasis.
Kimya Qaderi, Arvin Shahmoradi, Anita Thyagarajan, Ravi P. Sahu   +3 more
doaj   +2 more sources

Platelet activating factor revisited [PDF]

Thorax, 1997
8A2 and acetyltransferase on membrane alkylacyl phospholipids. PAF was found to possess many properties that made it well suited as a proinflammatory mediator of inflammation in many inflammatory diseases. 1 Interest in Degradation of PAF its potential role as a mediator of asthma was fuelled Being a potent bioactive mediator, it makes sense that PAF ...
Kian Fan Chung
openalex   +4 more sources

Advance in the pathogenesis of otitis media with effusion induced by platelet-activating factor. [PDF]

Sci Prog
Liu W, Shi L, Feng Y.
europepmc   +2 more sources

Platelet-Activating Factor Promotes the Development of Non-Alcoholic Fatty Liver Disease. [PDF]

Diabetes Metab Syndr Obes, 2022
Yin H, Shi A, Wu J.
europepmc   +3 more sources

PAF Physiology in Target Organ Systems—A Deep Dive to Understand the PAF Mystery in Pathogenesis of Disease

Hearts, 2021
The purpose of this literature review is to gain an overview of the role of platelet-activating factor (PAF) within each of the body systems and how it contributes to normal and pathophysiological states.
Nilank Shah, Karan Kumar, Nikeith Shah
doaj   +1 more source

The Platelet-Activating Factor Receptor’s Association with the Outcome of Ovarian Cancer Patients and Its Experimental Inhibition by Rupatadine

Cells, 2021
The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development.
Eileen Deuster, Ivi Hysenaj, Maja Kahaly, Elisa Schmoeckel, Doris Mayr, Susanne Beyer, Thomas Kolben, Anna Hester, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla   +14 more
doaj   +1 more source

UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment

Frontiers in Immunology, 2022
Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the major cause of skin carcinogenesis.
Timothy C. Frommeyer, Michael M. Gilbert, Garrett V. Brittain, Tongfan Wu, Trang Q. Nguyen, Craig A. Rohan, Craig A. Rohan, Craig A. Rohan, Jeffrey B. Travers, Jeffrey B. Travers, Jeffrey B. Travers   +10 more
doaj   +1 more source

Radiation therapy generates platelet-activating factor agonists [PDF]

, 2016
Pro-oxidative stressors can suppress host immunity due to their ability to generate oxidized lipid agonists of the platelet-activating factor-receptor (PAF-R).
Chin-Sinex, Helen Jan, Dynlacht, Joseph R., Garrett, Joy Elizabeth, Harrison, Kathleen A., Johnston II., Michael Edward, Konger, Raymond L., Li, Gengxin, McMullen, Kevin, Mendonca, Marc, Murphy, Robert C., Sahu, Ravi P., Spandau, Dan F., Travers, Jeffrey B., Weyerbacher, Jonathan   +13 more
core   +5 more sources

The Roles of Platelet-Activating Factor and Magnesium in Pathophysiology of Hypertension, Atherogenesis, Cardiovascular Disease, Stroke and Aging

Cardiogenetics, 2022
Hypertension and atherosclerosis are debilitating diseases that affect millions each year. Long-term consequences include but are not limited to stroke, myocardial infarction, and kidney failure.
Nilank Shah, Roshni Sethi, Sachin Shah, Komail Jafri, Jonah Duran, Yong Chang, Chirag Soni, Hanna Wollocko   +7 more
doaj   +1 more source