Results 281 to 290 of about 1,055,543 (397)

Physiologic impact of circulating RBC microparticles upon blood-vascular interactions [PDF]

, 2018
Doctor, Allan, Rogers, Stephen C, Said, Ahmed S   +2 more
core   +2 more sources

Copper and Iron‐Based Metal‐Organic Frameworks for Synergistic Cancer Phototherapies: Recent Advances, Challenges, and Future Prospects

Advanced Therapeutics, EarlyView.
The graphical abstract illustrates the combined effect of PTT and PDT using metal‐organic frameworks (MOFs) in a cancer treatment model. Tumor‐bearing mice are irradiated with different laser lights, which activate the MOF nanoparticles within cancer cells. The MOFs produce reactive oxygen species through PDT, while PTT elevates the temperature to kill
Kayalvizhi Samuvel Muthiah, Kalaiarasu Lakshminarayanan, Yu Chien Lin, Udesh Dhawan, Loganathan Rangasamy, Ren‐Jei Chung   +5 more
wiley   +1 more source

Clinical Values of Serum Platelet-Activating Factor in Hypertensive Disorders Complicating Pregnancy.

Kidney Blood Press Res
Liu S, Lan Q, Li W, Zhang J, Fu L, Xu Y, Li Y.   +6 more
europepmc   +1 more source

Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation. [PDF]

Lipids Health Dis
Hans S, Stanton JE, Sauer AK, Shiels K, Saha SK, Lordan R, Tsoupras A, Zabetakis I, Grabrucker AM.   +8 more
europepmc   +1 more source

Asymmetric synthesis of (+)- and (-)-batyl alcohol, a key synthetic intermediate for platelet-activating factor, by using biocatalysts.

, 1987
Hiroshi Suemune, Yukako Mizuhara, Hiroyuki Akita, Takeshi Oishi, Kiyoshi Sakai   +4 more
openalex   +2 more sources

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

The PFI-index according to Aasen for prognosis and course of polytraumatized patients [PDF]

, 1988
Baumgartner, I., Duswald, Karl-Heimo, Jochum, Marianne, Nast-Kolb, Dieter, Redl, H., Schlag, G., Schweiberer, Leonhard, Waydhas, Christian   +7 more
core  

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

Investigation of the involvement of platelet-activating factor in the control of hypertension by aerobic training. A randomized controlled trial. [PDF]

Biol Sport
Prado JP, Castro AE, Carvalho J, Pereira D, Faccioli LH, Sorgi C, Novaes R, Silva S, Galdino G.   +8 more
europepmc   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source