Results 261 to 270 of about 115,616 (306)

Platelet-activating factor and asthma

Journal of Allergy and Clinical Immunology, 1988
anaphylaxis. And if you research into the 1920s) there a very useful treatment in blocking both thrombocyare articles, particularly in the German literature, that topenia and some of the features of anaphylaxis. The report thrombocytopenia as being a feature of clinical first article (1924) stated that heparin totally prevents asthma.
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Platelet-Activating Factor and Platelet-Activating Factor Antagonists in Acute Pancreatitis

Digestive Surgery, 1999
<i>Introduction:</i> Acute pancreatitis causes platelet-activating factor (PAF) to be released which induces systemic effects that contribute to circulatory disturbances and multiple organ failure. PAF has also been implicated as a key mediator in the progression of severe acute pancreatitis, which can lead to complications and unacceptably
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Platelet Activating Factor and Conception

American Journal of Reproductive Immunology, 1996
PURPOSE: This review provides evidence for the involvement of platelet activating factor (PAF) in the several facets of pregnancy establishment.METHODS: A comprehensive literature review and new data.RESULTS: PAF has a role in spermatozoal function, fertilization, embryo development, and implantation.CONCLUSIONS: PAF is intimately involved in ...
B S, Minhas, B A, Ripps, Y P, Zhu, H N, Kim, T H, Burwinkel, N, Gleicher   +5 more
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Seminal Platelet-Activating Factor

Seminars in Thrombosis and Hemostasis, 2007
Platelet-activating factor (PAF; 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphorylcholine) is a potent signaling phospholipid with pleiotropic biologic activities. Since its discovery more than 30 years ago, numerous investigators have documented its presence in a variety of tissues.
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Platelet-Activating Factor and Angiogenesis

1996
Platelet-activating factor (PAF) is a phospholipid autacoid with a spectrum of diverse and potent biological properties relevant for the development of inflammatory reaction and septic shock1. Recently, PAF has been also implicated in the embryogenesis and cell differentiation2,3. Researchers believe that PAF is a mediator of cell to cell communication
G, Camussi, G, Montrucchio, E, Lupia, M, Arese, F, Bussolino   +4 more
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The role of platelet-activating factor in platelet aggregation

Nature, 1979
PLATELET aggregation is mediated by at least three distinct mechanisms1,2. The first involves the release of ADP and is inhibited by its conversion to ATP by the combination of creatine phosphate and creatine phosphokinase (CP/CPK). The second is mediated by metabolites of arachidonic acid, particularly thromboxane A2 (TXA2), and is blocked by aspirin ...
M, Chignard, J P, Le Couedic, M, Tence, B B, Vargaftig, J, Benveniste   +4 more
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Desensitization of human platelets by platelet activating factor

Biochemical and Biophysical Research Communications, 1985
Human platelets are less responsive to PAF at 37 degrees than at 25 degrees. They can be desensitized to the effects of PAF by pre-exposure to small concentrations. In both cases desensitization appears to be accompanied by a decreased affinity of the high affinity site for PAF rather than loss of binding sites.
C M, Chesney, D D, Pifer, K M, Huch
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Platelet Activating Factor Receptors

2003
Platelet activating factor (PAF) is a potent pro-inflammatory lipid mediator. Its effects are mediated through cell surface G protein-coupled receptors (GPCRs) that are distributed on numerous cells notably on endothelium [1]. An intracrine mode of action for PAF is proposed based on evidence for intracellular PAF binding sites [2] and retention of ...
A Marilise, Marrache, Fernand, Gobeil, Sylvie G, Bernier, Jana, Stankova, Marek, Rola-Pleszczynski, Sanaa, Choufani, Ghassan, Bkaily, Annie, Bourdeau, Martin G, Sirois, Alejandro, Vazquez-Tello, L, Fan, Jean-Sebastien, Joyal, Janos G, Filep, Daya R, Varma, Alfredo, Ribeiro-Da-silva, Sylvain, Chemtob   +15 more
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Platelet Factor 3 Activity in Washed Platelets

Thrombosis and Haemostasis, 1973
SummaryPlatelets collected with an EDTA solution and simply washed in an incomplete Tyrode’s presented clotting times in the recalcification (man and rat) and the Stypven (rat) tests that were practically identical to those of the PRP when slow speed centrifugation was used (800 G in man, 1000 G in rat). This was demonstrated, in 6 pools of 5 rats each
S, Renaud, P, Gautheron, H, Rosenstein
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Platelet Microparticles: A Carrier of Platelet-Activating Factor?

Biochemical and Biophysical Research Communications, 1996
Platelet-activating factor (PAF) has been considered to be released in a soluble form from activated platelets. Also a considerable number of microparticles were released from stimulated platelets. To evaluate the possibility that microparticles contain PAF, the amount of PAF in whole activated platelets, microparticles and the suspending medium was ...
S, Iwamoto, T, Kawasaki, J, Kambayashi, H, Ariyoshi, M, Monden   +4 more
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