Results 241 to 250 of about 115,616 (306)

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

open access: yesAdvanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che   +9 more
wiley   +1 more source

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li   +14 more
wiley   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

open access: yesAdvanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang   +10 more
wiley   +1 more source

Comparison of the Actions of Some Platelet-Activating Factor Antagonists on Platelets and Aortic Smooth Muscles

open access: yes, 2008
TENG, CHE-MING;YU, SHEU-MEEI;YU, SHEU-MEEI;KO, FENG-NIEN;CHEN, CHIEN-CHIH;WANG, WEN-CHUNG;HUANG, YU-LING;CHEN, KUAN-YU;HUANG, TUR-FU   +1 more
core  

Platelet activating factor enhances in vitro fertilization of rabbit oocytes

open access: yesAmerican Journal of Obstetrics and Gynecology, 1990
Capacitation of spermatozoa is essential for fertilization. Rabbit spermatozoa are particularly difficult to capacitate in vitro and require treatment with high-ionic-strength Brackett\u27s defined medium.
William E Roudebush, Brijinder S Minhas
exaly   +2 more sources

Effects of platelet activating factor on mouse oocyte fertilization in vitro

open access: yesAmerican Journal of Obstetrics and Gynecology, 1989
Platelet activating factor is rapidly gaining acceptance as a potent mediator in many reproductive processes. This study presents data that indicate a direct role of platelet activating factor in fertilization.
Brijinder S Minhas   +2 more
exaly   +2 more sources

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