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Associations between healthy food groups and platelet-activating factor, lipoprotein-associated phospholipase A₂ and C-reactive protein: a cross-sectional study. [PDF]

Eur J Nutr
English CJ, Jones M, Lohning AE, Mayr HL, MacLaughlin H, Reidlinger DP.   +5 more
europepmc   +1 more source

[Relationship Between Neonatal Outcomes and Changes in Serum Platelet-Activating Factor, Fibulin-3, and Umbilical Artery Blood Flow During Late Pregnancy in Pregnant Women With Gestational Hypertension]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Sun Y, Zhang H, Sun L.
europepmc   +1 more source

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Platelet-Activating Factor

Scandinavian Journal of Gastroenterology, 1996
Platelet-activating factor (PAF) is a proinflammatory lipid. It has been strongly implicated in the regulation of pancreatic exocrine secretion and in the local and systemic events which occur in acute pancreatitis. PAF antagonists, when given as pretreatment, ameliorate the severity of experimental acute pancreatitis by reducing serum amylase ...
A N Kingsnorth
exaly   +3 more sources

Platelet-activating factor and the kidney

American Journal of Physiology-Renal Physiology, 1986
Platelet-activating factor (PAF) represents a group of phospholipids with the basic structure of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine. A number of different cells are capable of producing PAF in response to various stimuli. The initial step of PAF formation is activation of phospholipase A2 in a calcium-dependent manner, yielding lyso-PAF ...
D, Schlondorff, R, Neuwirth
openaire   +3 more sources

The role of platelet-activating factor in platelet aggregation

Nature, 1979
PLATELET aggregation is mediated by at least three distinct mechanisms1,2. The first involves the release of ADP and is inhibited by its conversion to ATP by the combination of creatine phosphate and creatine phosphokinase (CP/CPK). The second is mediated by metabolites of arachidonic acid, particularly thromboxane A2 (TXA2), and is blocked by aspirin ...
M, Chignard, J P, Le Couedic, M, Tence, B B, Vargaftig, J, Benveniste   +4 more
openaire   +3 more sources

Platelet Activating Factor (PAF): A Mediator of Inflammation

Biofactors, 2022
Platelet‐activating factor (PAF) is a phospholipid‐derived mediator with an established role in multiple inflammatory states. PAF is synthesized and secreted by multiple cell types and is then rapidly hydrolyzed and degraded to an inactive metabolite ...
J. Upton, E. Grunebaum, G. Sussman, P. Vadas   +3 more
semanticscholar   +1 more source

Platelet Activating Factor: A Biologically Active Phosphoglyceride

Annual Review of Biochemistry, 1986
D. Hanahan
openaire   +3 more sources

Radioimmunoassay for platelet‐activating factor

Lipids, 1991
AbstractA radioimmunoassay (RIA) for measurement of platelet‐activating factor (PAF) was developed. At a final antiserum dilution of 1∶640, the lowest detection limit of PAF was 0.1 pmol (50 pg). The standard curve obtained was suitable for measurement of PAF in amounts ranging from 0.1 pmol to 30 pmol. The antiserum showed high specificity.
K, Karasawa, N, Satoh, T, Hongo, Y, Nakagawa, M, Setaka, S, Nojima   +5 more
openaire   +2 more sources

Platelet-activating factor receptor

Prostaglandins & Other Lipid Mediators, 2002
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was named for its potential to induce platelet aggregation, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues.
Zen-ichiro, Honda, Satoshi, Ishii, Takao, Shimizu   +2 more
openaire   +3 more sources