Results 61 to 70 of about 991,613 (310)

Circulating biologically active oxidized phospholipids show on-going and increased oxidative stress in older male mice

Redox Biology, 2013
Background: The biologically active phospholipids Platelet-activating Factor (PAF) and oxidatively truncated phospholipids from chemical oxidation are increased in the circulation of rats subject to the oxidant stress of chronic ethanol ingestion ...
Jinbo Liu, Wei Li, Rui Chen, Thomas M. McIntyre   +3 more
doaj   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Macrophage Derived Platelet Activating Factor Implicated in the Resolution Phase of Gouty Inflammation

International Journal of Inflammation, 2014
Human blood derived in vitro differentiated monocytes or macrophages are a population of cells which have been investigated over the years to determine the role these cells play in the resolution phase of gout.
Darshna Yagnik
doaj   +1 more source

Modulation by flavonoids of PAF and related phospholipids in endothelial cells during oxidative stress

Journal of Lipid Research, 2003
PAF-dependent transacetylase (TA) modifies the functions of platelet-activating factor (PAF), a potent inflammatory lipid, either by transferring the acetyl group from PAF to lysophospholipids (TAL activity), or to sphingosine (TAS activity) or by ...
Maria Luisa Balestrieri, Domenico Castaldo, Ciro Balestrieri, Lucio Quagliuolo, Alfonso Giovane, Luigi Servillo   +5 more
doaj   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

The emerging roles of PAF acetylhydrolase

Journal of Lipid Research, 2009
Platelet-activating factor (PAF), a phospholipid autacoid with potent effects throughout the innate immune system, is selectively degraded by two small families of PAF acetylhydrolases (PAF-AHs).
Thomas M. McIntyre, Stephen M. Prescott, Diana M. Stafforini   +2 more
doaj   +1 more source

Specific binding of phospholipid platelet-activating factor by human platelets.

Journal of Immunology, 1982
The binding of the phospholipid platelet-activating factor 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine (AGEPC) to washed human platelets was more than 80% complete within 2 min, which coincided with the time of initiation of platelet ...
F. Valone, E. Coles, V. R. Reinhold, E. Goetzl   +3 more
semanticscholar   +1 more source

Therapeutic effects of intranasal tocotrienol-rich fraction on rhinitis symptoms in platelet-activating factor induced allergic rhinitis [PDF]

, 2022
Cheryl Wei Ling Teo, Stephanie Jia Ying Png, Yee Wei Ung, Wei Ney Yap   +3 more
openalex   +1 more source

Insight into the Internal Structure of Biogenic, Synthetic and Geological Apatite by Electron Microscopy and X‐Ray Scattering

Advanced Functional Materials, EarlyView.
Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka, Oleg Prymak, Kateryna Loza, Matthias Epple   +3 more
wiley   +1 more source