Platelet-derived growth factor promotes polymorphonuclear leukocyte activation [PDF]
DY Tzeng+5 more
openalex +1 more source
Neural Operator Modeling of Platelet Geometry and Stress in Shear Flow [PDF]
Thrombosis involves processes spanning large-scale fluid flow to sub-cellular events such as platelet activation. Traditional CFD approaches often treat blood as a continuum, which can limit their ability to capture these microscale phenomena. In this paper, we introduce a neural operator-based surrogate model to bridge this gap.
arxiv
Air-blood interface engineered microfluidic device to mimic shear rate gradient induced human bleeding model [PDF]
Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over channel geometry and flow conditions.
arxiv
Alterations in 32P-labelled intermediates during flux activation of human platelet glycolysis [PDF]
Jan-Willem Akkerman+3 more
openalex +1 more source
Phospholipase abolishes the effect of stimulated platelets on the thrombin activation of factor VIII [PDF]
ME Rick, DM Krizek
openalex +1 more source
The bile acid receptor TGR5 inhibits platelet activation and thrombus formation
Liver failure and cirrhosis are characterized by abnormal hemostasis with aberrant platelet activation. In particular, the consequences of cholestatic liver disease and molecular mechanisms, including the role of bile acids leading to impaired platelet ...
Friedrich Reusswig+5 more
doaj +1 more source
Venom coagglutinin: an activator of platelet aggregation dependent on von Willebrand factor.
Marjorie S. Read+2 more
openalex +1 more source
Synergistic inhibition of platelet activation by plasmin and prostaglandin I2 [PDF]
AI Schafer+3 more
openalex +1 more source
Activation of platelets plays a crucial role in the pathophysiology of thrombosis and hemostasis. Blood test reflecting in vivo platelet activation is therefore potentially useful in evaluating patients with thrombosis.
Nungruthai Nimnuch+1 more
doaj
Carotid endarterectomy in patients with heparin-induced platelet activation: Comparative efficacy of aspirin and iloprost (ZK36374) [PDF]
Jeffrey R. Kappa+6 more
openalex +1 more source