Results 131 to 140 of about 4,071,532 (408)

Functional responses and molecular mechanisms involved in histone-mediated platelet activation

Thrombosis and Haemostasis, 2013
Summary Histones are highly alkaline proteins found in cell nuclei and they can be released by either dying or inflammatory cells. The recent observations that histones are major components of neutrophil extracellular traps and promote platelet ...
Agostina Carestia, L. Rivadeneyra, M. Romaniuk, C. Fondevila, S. Negrotto, M. Schattner   +5 more
semanticscholar   +1 more source

The platelet-activating factor acetylhydrolase of mouse platelets

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1997
Platelet-activating factor (PAF) acetylhydrolases are a family of distinct enzymes with the common property of hydrolyzing and inactivating PAF. It has been shown that the structure and the biochemical behavior of these enzymes depend on their cellular origin.
Angeliki P Karpouza, Catherine Vakirtzi-Lemonias   +1 more
openaire   +3 more sources

Mesoporous Silica Microspheres by Super‐Fast Alkaline Etching of Micrometer‐Sized Stöber Particles

Advanced Engineering Materials, EarlyView.
Microscale silica particles are prepared along with a modified, scalable Stöber synthesis using the continuous addition of tetraethoxy silane to an ethanolic solution of ammonia with KCl. Etching with hydroxide ions at 95 °C gave porous analogs within minutes. Monodisperse particles are isolable in high yield after precipitation in ethanol.
Adrian Vaghar, Georgij Jegorenkov, Gerrit A. Luinstra   +2 more
wiley   +1 more source

Receptors that Activate Platelets

Experimental Biology and Medicine, 1991
This review highlights the increasing knowledge of the biochemistry, pathology, and cell and molecular biology of platelet receptors. A receptor for ADP has been identified using the affinity label FSBA as aggregin, a 100-kDa membrane protein responsible for shape change, aggregation, and exposure of fibrinogen binding sites.
openaire   +3 more sources

Comparison of three commercially available buffy coat pooling sets for the preparation of platelet concentrates [PDF]

, 2018
Background: A disposable set for platelet concentrate (PC) preparation by the buffy coat method allows pooling of buffy coats, centrifugation and cell separation with in-line leucocyte filtration.
Aelst, Aelst, Drawz, Feys, Goodall, Hardwick, Hild, Irsch, Krailadsiri, Meer, Metcalfe, Vanaudenaerde   +11 more
core   +2 more sources

Sol–Gel Synthesis of Ca2.5Ag0.3Sm0.2Co4O9 Semiconducting Materials for Thermoelectric Applications in Aerospace Systems

Advanced Engineering Materials, EarlyView.
Ca2.5Ag0.3Sm0.2Co4O9 semiconductor materials are synthesized and produced in this study using the sol–gel and cold pressing techniques for thermoelectric generator applications. As template samples are added, the Seebeck coefficient and power factor values rise, peaking at 800 °C for Ca2.5Ag0.3Sm0.2Co4O9 at 274.47 μV K−1 and 0.58 mW mK−2, respectively.
Enes Kilinc, Fatih Uysal, Mucahit Abdullah Sari, Huseyin Kurt, Erdal Celik   +4 more
wiley   +1 more source

Inhibition of Platelet Activation by Clopidogrel Prevents Hypertension-Induced Cardiac Inflammation and Fibrosis

Cardiovascular Drugs and Therapy, 2013
PurposePlatelets are essential for primary hemostasis; however, platelet activation also plays an important proinflammatory role. Inflammation promotes the development of cardiac fibrosis and heart failure induced by hypertension. In this study, we aimed
Li-xin Jia, Guanming Qi, Ou Liu, Taotao Li, Min Yang, W. Cui, Wenmei Zhang, Y. Qi, Jie Du   +8 more
semanticscholar   +1 more source

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]

, 2018
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A., Kaplan, Mark H., Ocana, Jesus A., Pawelzik, Sven-Christian, Romer, Eric, Sahu, Ravi, Travers, Jeffrey B.   +6 more
core   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

The effects of arterial flow on platelet activation, thrombus growth, and stabilization.

Cardiovascular Research, 2013
Injury of an arterial vessel wall acutely triggers a multifaceted process of thrombus formation, which is dictated by the high-shear flow conditions in the artery. In this overview, we describe how the classical concept of arterial thrombus formation and
J. Cosemans, A. Angelillo-Scherrer, N. Mattheij, J. Heemskerk   +3 more
semanticscholar   +1 more source