Results 151 to 160 of about 287,515 (269)

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Platelet activation plays a pro-inflammatory role in myasthenia gravis. [PDF]

Nat Commun
Wen Q, Zhang S, Wang Y, Liu H, Wang J, Su S, Xie N, Lu Y, Di L, Xu M, Wang M, Chen H, Wang S, Zhu W, Wen X, Han J, Wan D, Zhao S, Lu W, Tao Z, Duo J, Huang Y, Chai G, Duan R, Li X, Hao J, Da Y.   +26 more
europepmc   +1 more source

Seedless One‐Pot Synthesis of Colloidal InAs Quantum Dots Enabling a High‐Accuracy Photoplethysmography Oximeter

Advanced Science, EarlyView.
A real‐time, non‐contact photoplethysmography (PPG) system based on InAs colloidal quantum dots (CQDs) synthesized via a seedless injection synthesis is demonstrated. The measured oxygen saturation shows considerable agreement with commercial PPG devices.
Beom Kwan Kim, Seungin Jee, Yongnam Ahn, In‐Suh Lee, Dongeon Kim, Seongchong Park, Yujin Jung, In‐Ho Bae, Se‐Woong Baek   +8 more
wiley   +1 more source

Selection and optimization strategy for Rap1-targeting single-domain antibodies as platelet activation markers. [PDF]

Res Pract Thromb Haemost
Alessi MC, Moulard M, Boulay-Moine D, Pons C, Margier M, Vessière C, Poggi M, Pigaglio T, Dignat-George F, Roussel A, Burtey S, Bonello L, Chames P, Bonjean R, Peiretti F.   +14 more
europepmc   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Ginsenoside Rs3 (G-Rs3) inhibits agonist- and oxLDL-mediated platelet activation and attenuates <i>in vivo</i> arterial thrombosis. [PDF]

J Ginseng Res
Shin JH, Akram AW, Saba E, Kim MC, Kim SD, Park SJ, Kwak D, Kwon HW, Rhee MH.   +8 more
europepmc   +1 more source

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

Advanced Science, EarlyView.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen, Hanjie Zhu, Yue Zhang, Yuqing Qiao, Ruotong Deng, Huaping Xu, Wei Cao   +6 more
wiley   +1 more source

Graft-derived VWF drives platelet activation and thrombocytopenia during porcine liver xenotransplantation to brain-dead human recipients. [PDF]

J Clin Invest
Zhao L, Apostolidis SA, Suzuki A, Sarkar A, Guo Q, Li F, Sagar A, Fallon J, Elzawahry MA, Abbas SH, Lanieri L, Getchell K, Low SC, Olthoff KM, Furth EE, Keating BJ, Friend P, Poncz M, Shaked A, Abrams CS.   +19 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Lauryl gallate promotes platelet activation and thrombus formation: a promising application to stop bleeding. [PDF]

Clin Sci (Lond)
Hadjkacem B, Garcia C, Series J, Pons V, Mahmoudi A, Gales C, Voisin S, Ribes A, Gratacap MP, Gargouri A, Payrastre B.   +10 more
europepmc   +1 more source