Results 151 to 160 of about 4,071,532 (408)
Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction [PDF]
The MEK inhibitors cobimetinib and trametinib are used in combination with BRAF inhibitors to treat metastatic melanoma but increase rates of hemorrhage relative to BRAF inhibitors alone.
Bye, Alex P.+6 more
core +4 more sources
Intercalation of a series of FeSe1−xSx host crystals with tetramethylammonium cations (TMA+) linearly scales the critical temperature Tc from 43 K down to 28 K with increasing sulfur incorporation. The chemical pressure induced by the partial substitution shows a weakening of the superconducting properties in both hosts and intercalates in a remarkably
Nadine Lammer+3 more
wiley +1 more source
Role of platelets and platelet receptors in cancer metastasis
The interaction of tumor cells with platelets is a prerequisite for successful hematogenous metastatic dissemination. Upon tumor cell arrival in the blood, tumor cells immediately activate platelets to form a permissive microenvironment.
M. Schlesinger
semanticscholar +1 more source
Defective ADP-Induced Platelet Factor 3 Activation in Uremia [PDF]
Herbert I. Horowitz+3 more
openalex +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Modulation of Platelet Activation by Native DNA [PDF]
B A Fiedel+2 more
openalex +1 more source
Background 3-Hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been widely used to reduce cardiovascular risk. These statins (i.e., simvastatin) may exert other effects besides from their cholesterol-lowering actions ...
Hou Ssu-Yu+7 more
doaj +1 more source
Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]
Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW+18 more
core +1 more source
Bi‐directionally assembled BN µ‐platelets in micropatterns formed by a micro‐molding method for thermal interface materials are demonstrated. The BN µ‐platelets are vertically aligned selectively, while compressed regions without patterns accommodate horizontally assembled BN µ‐platelets. Through anisotropic orientation, high thermal conductivities for
Young Gil Kim+12 more
wiley +1 more source
Nanoparticle biointerfacing via platelet membrane cloaking
Development of functional nanoparticles can be encumbered by unanticipated material properties and biological events, which can affect nanoparticle effectiveness in complex, physiologically relevant systems.
C. J. Hu+21 more
semanticscholar +1 more source