Results 241 to 250 of about 467,395 (313)

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

NR4A1 Acts as a Novel Regulator of Platelet Activation and Thrombus Formation. [PDF]

Circ Res
Liu W, Li G, Shi J, Gao Y, Fang P, Zhao Y, Zhong F, Guo X, Lyu Y, Da X, Li Z, Fa J, Hu L, Yuan A, Chen L, Liu J, Chen AF, Sheng B, Ji Y, Lu X, Pu J.   +20 more
europepmc   +1 more source

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Thiol isomerase ERp18 enhances platelet activation and arterial thrombosis. [PDF]

Res Pract Thromb Haemost
He C, Yang A, Lv K, Zhang Y, Zhao Z, Lu Y, Fang C, Han Y, Wu D, Jiang M, Zhang J, Wu Y.   +11 more
europepmc   +1 more source

Procoagulant platelet activation promotes venous thrombosis.

Blood
Kaiser R, Dewender R, Mulkers M, Stermann J, Rossaro D, Di Fina L, Li L, Gold C, Schmid M, Kääb L, Eivers L, Akgöl S, Yue K, Kammerer L, Loew Q, Anjum A, Escaig R, Akhalkatsi A, Laun L, Kranich J, Brocker T, Mueller TT, Krächan A, Gmeiner J, Pekayvaz K, Thienel M, Massberg S, Stark K, Kilani B, Nicolai L.   +29 more
europepmc   +1 more source

Recurrent hypoglycemia exposure increases the risk of platelet activation and thrombosis in insulin-treated diabetic rats. [PDF]

Diabetes Obes Metab
Rehni AK, Cho S, Liu A, Lo J, Kim SS, Khoury N, Perez-Pinzon MA, Jy W, Dave KR.   +8 more
europepmc   +1 more source

Perceived Stress is Associated with Health Outcomes, Platelet Activation, and Oxidative Stress in COPD. [PDF]

Chronic Obstr Pulm Dis
Offor O, Eakin MN, Woo H, Belz D, Williams M, Raju S, McCormack M, Hansel NN, Putcha N, Fawzy A.   +9 more
europepmc   +1 more source

Elevated IL-1 Beta Plasma Levels, Altered Platelet Activation and Cardiac Remodeling Lead to Moderately Decreased LV Function in Alzheimer Transgenic Mice After Myocardial Ischemia and Reperfusion. [PDF]

J Cardiovasc Dev Dis
Donner L, Gorressen S, Fischer JW, Elvers M.   +3 more
europepmc   +1 more source

Synergistic Promotion of Triple-Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella-Derived Glutamate and Platelet Activation. [PDF]

Adv Sci (Weinh)
Zhu L, Xu P, Zhou M, Li K, Tian S, Fan X, Liu J, Ye B, Ding Z, Shen Y.   +9 more
europepmc   +1 more source

Direct Interleukin-6 Inhibition Blunts Arterial Thrombosis by Reducing Collagen-Mediated Platelet Activation. [PDF]

Arterioscler Thromb Vasc Biol
Ministrini S, Liberale L, Puspitasari YM, Han J, Kirmes K, Unkelbach LP, Tirandi A, Niederberger R, Bengs S, Beer JH, Montecucco F, Libby P, Lüscher TF, Bongiovanni D, Camici GG.   +14 more
europepmc   +1 more source