Results 151 to 160 of about 12,292 (326)
USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen +9 more
wiley +1 more source
Platelet Functional Profile Is Altered in Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]
Castelli M +6 more
europepmc +1 more source
Effect of carbocromen on the adhesiveness and aggregation of human platelets
Yasuyuki Endo, Akira Shibata
openalex +2 more sources
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang +6 more
wiley +1 more source
Platelets During Myelin Repair in Multiple Sclerosis: Friend or Foe? [PDF]
Rivera FJ +4 more
europepmc +1 more source
Breast cancer reprograms the lung into a receptive pre‐metastatic niche via a novel G‐CSF–VEGFA–KDR signaling axis. Using a micro‐organ chip that enables contact‐independent coculture, this study uncovers how tumor‐secreted G‐CSF activates lung capillary KDR to drive angiogenesis and prime the soil for metastasis—without direct tumor contact.
Jingxin Zhang +12 more
wiley +1 more source
The nonconserved integrin cytoplasmic region determines integrin subtype-specific characteristics by modulating talin1 binding kinetics. [PDF]
Kondo N +7 more
europepmc +1 more source
Platelet adhesiveness in patients with prosthetic heart valves
M Aosaki +7 more
openalex +2 more sources

